Optimized Ebselen-Based Inhibitors of Bacterial Ureases with Nontypical Mode of Action
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DOI: 10.1021/acs.jmedchem.2c01799
Abstract: Screening of 25 analogs of Ebselen, diversified at the N-aromatic residue, led to the identification of the most potent inhibitors of Sporosarcina pasteurii urease reported to date. The presence of a dihalogenated phenyl ring caused… read more here.
Keywords: ureases nontypical; ebselen based; bacterial ureases; inhibitors bacterial ... See more keywords