Anti-pruritic effect of nemolizumab in hemodialysis patients with uremic pruritus: a phase II, randomized, double-blind, placebo-controlled clinical study
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-021-02047-2
Abstract: The pathophysiology of uremic pruritus (UP), which is characterized by systemic and intractable itching, remains unclear. As interleukin (IL)-31 may be involved, we conducted a phase II, randomized, controlled study to evaluate nemolizumab (anti-IL-31 receptor… read more here.
Keywords: phase; study; uremic pruritus; phase randomized ... See more keywords
A successful case of dupilumab treatment for severe uremic pruritus
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DOI: 10.1016/j.jdcr.2019.01.024
Abstract: IL: interleukin NBUVB: narrow-band ultraviolet B phototherapy UP: uremic pruritus U remic pruritus (UP) is highly burdensome and difficult to treat. Previous studies implicated interleukin (IL)-31 in the pathogenesis of UP. IL-31 expression is upregulated… read more here.
Keywords: case dupilumab; pruritus; case; uremic pruritus ... See more keywords
Recent advances in the treatment of uremic pruritus.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in nephrology and hypertension"
DOI: 10.1097/mnh.0000000000000625
Abstract: PURPOSE OF REVIEW This article provides a focused update on uremic pruritus, highlighting the latest evidence concerning the epidemiology, pathophysiology, and treatment options for this common and bothersome condition. RECENT FINDINGS Half of dialysis patients… read more here.
Keywords: treatment uremic; pruritus; uremic pruritus; recent advances ... See more keywords
UPLC-QTOF MS-Based Serum Metabolomic Profiling Analysis Reveals the Molecular Perturbations Underlying Uremic Pruritus
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DOI: 10.1155/2018/4351674
Abstract: As one of the most troublesome complications in patients with chronic renal disease, the etiology of uremic pruritus remains unknown, and the current therapeutic approaches are limited and unsatisfactory. To identify potential biomarkers for improving… read more here.
Keywords: profiling; lup patients; analysis; pruritus ... See more keywords
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Nalbuphine ER Tablets for Uremic Pruritus
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Nephrology"
DOI: 10.1159/000484573
Abstract: Background: Pruritus is a distressing hallmark of the uremic condition, affecting approximately 60% of hemodialysis patients. Abnormal endogenous opioid ligand activity at μ and κ-opioid receptors has been postulated as a mechanism in uremic pruritus.… read more here.
Keywords: pruritus; controlled trial; uremic pruritus; nal 120 ... See more keywords
Evaluation of serum levels of neurotrophin 4 and brain-derived nerve growth factor in uremic pruritus patients
Sign Up to like & getrecommendations! Published in 2019 at "Clinical, Cosmetic and Investigational Dermatology"
DOI: 10.2147/ccid.s190917
Abstract: Background Pruritus is a common symptom in end-stage renal failure. Many patients suffer from this severe distressing symptom. Although several factors have been postulated to explain uremic pruritus, there is not any conclusive evidence for… read more here.
Keywords: uremic patients; serum; uremic pruritus; serum levels ... See more keywords
Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of
Sign Up to like & getrecommendations! Published in 2017 at "Therapeutics and Clinical Risk Management"
DOI: 10.2147/tcrm.s129133
Abstract: Uremic pruritus (UP) is a common and incapacitating symptom in patients undergoing hemodialysis (HD). The pathogenesis of UP is multifactorial and complex. Particulate matter (PM), a major air pollutant, is a mixture of particles with… read more here.
Keywords: mean hour; uremic pruritus; number; number days ... See more keywords
Validity and reliability of Persian Version of 12-Item Pruritus Severity Score Questionnaire in the Hemodialysis Patients with Uremic Pruritus
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Dermatology"
DOI: 10.22034/ijd.2021.221589.1036
Abstract: Background: The 12-Item Pruritus Severity Scale (12-PSS) is a multidimensional tool that evaluates pruritus intensity and duration along with an assessment of psychometric properties such as the patient´s mood, daily activities, and sleep pattern. Given… read more here.
Keywords: hemodialysis patients; validity reliability; uremic pruritus; validity ... See more keywords
Clinical Efficacy and Safety of Chinese Herbal Medicine in the Treatment of Uremic Pruritus: A Meta-Analysis of Randomized Controlled Trials
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15101239
Abstract: Uremic pruritus is a disturbing and refractory symptom in patients with advanced chronic kidney disease. Chinese herbal medicine has been reported to alleviate uremic pruritus. To investigate the effects of Chinese herbal medicine, we conducted… read more here.
Keywords: herbal medicine; uremic pruritus; meta analysis; chinese herbal ... See more keywords
A controlled trial of narrowband ultraviolet B phototherapy for the treatment of uremic pruritus
Sign Up to like & getrecommendations! Published in 2017 at "Indian Journal of Dermatology, Venereology and Leprology"
DOI: 10.4103/0378-6323.198464
Abstract: The study group comprised thirty consecutive patients with Stage IV and V chronic renal disease who attended the outpatient clinic of Government Medical College, Kozhikode. from April 2012 to March 2013. They were referred from… read more here.
Keywords: pruritus; study; controlled trial; uremic pruritus ... See more keywords