Effect of Continuous Intravenous Calcium Loading on Fibroblast Growth Factor 23 in Normal and Uremic Rats
Sign Up to like & getrecommendations! Published in 2018 at "Calcified Tissue International"
DOI: 10.1007/s00223-018-0440-2
Abstract: Fibroblast growth factor 23 (FGF23) is associated with mortality in patients with CKD. However, the mechanisms underlying stimulation of FGF23 remain to be investigated. We examined whether hypercalcemia induced by continuous intravenous (CIV) calcium (Ca)… read more here.
Keywords: fgf23; uremic rats; fibroblast growth; normal uremic ... See more keywords
Puerarin inhibits vascular calcification of uremic rats.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.05.023
Abstract: The risk of cardiovascular events in patients with chronic kidney disease is tremendously increased due to vascular calcification. Local vascular inflammation significantly promotes vascular calcification. A previous study has shown that puerarin inhibits calcification of… read more here.
Keywords: calcification uremic; puerarin inhibits; vascular calcification; uremic rats ... See more keywords
Bone marrow-derived cells and their conditioned medium induce microvascular repair in uremic rats by stimulation of endogenous repair mechanisms
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09883-x
Abstract: The reduced number of circulating stem/progenitor cells that is found in chronic kidney disease (CKD) patients may contribute to impaired angiogenic repair and decreased capillary density in the heart. Cell therapy with bone marrow-derived cells… read more here.
Keywords: conditioned medium; marrow derived; uremic rats; derived cells ... See more keywords
The use of LP533401 as a therapeutic option for renal osteodystrophy affects, renal calcium handling, vitamin D metabolism, and bone health in uremic rats
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2019.1586883
Abstract: ABSTRACT Background: Klotho is a key regulator of phosphate and Ca2+-transport in the kidney. Recently, we showed that treatment with LP533401 improved bone health in rats with chronic kidney disease (CKD) via the normalization of… read more here.
Keywords: uremic rats; renal calcium; calcium handling; bone health ... See more keywords
Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Medicine"
DOI: 10.1186/s10020-019-0110-5
Abstract: BackgroundPeritoneal fibrosis (PF) represents a long-term complication of peritoneal dialysis (PD), affecting peritoneal membrane (PM) integrity and function. Understanding the mechanisms underlying PF development in an uremic environment aiming alternative therapeutic strategies for treating this… read more here.
Keywords: fibrosis; model developed; uremic rats; developed uremic ... See more keywords