Effective clearance of uremic toxins using functionalised silicon Nanoporous membranes
Sign Up to like & getrecommendations! Published in 2021 at "Biomedical Microdevices"
DOI: 10.1007/s10544-020-00539-8
Abstract: In-house fabricated silicon nanoporous membranes (SNMs), functionalized for efficient clearance of uremic toxins, can lead to compact and portable dialysis systems. Efficacy of 15 nm thick SNMs, with average pore diameter of 8 nm, was tested for… read more here.
Keywords: uremic toxins; clearance uremic; urea creatinine; nanoporous membranes ... See more keywords
Effects of Probiotics on Inflammation and Uremic Toxins Among Patients on Dialysis: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2018 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-018-5243-9
Abstract: Background/ObjectivesWe performed this systematic review and meta-analysis to evaluate effects of probiotics on inflammation, uremic toxins, and gastrointestinal (GI) symptoms in end-stage renal disease (ESRD) patients.MethodsA literature search was conducted utilizing MEDLINE, EMBASE, and Cochrane… read more here.
Keywords: uremic toxins; inflammation uremic; effects probiotics; probiotics inflammation ... See more keywords
Uremic toxins levels from the gut microbiota seem not to be altered by physical exercise in hemodialysis patients
Sign Up to like & getrecommendations! Published in 2021 at "International Urology and Nephrology"
DOI: 10.1007/s11255-021-02945-0
Abstract: Regular physical exercise may result in many benefits to patients with chronic kidney disease (CKD) on hemodialysis (HD), including gut microbiota modulation and solute removal. The study aimed to evaluate the effects of two programs… read more here.
Keywords: uremic toxins; hemodialysis; gut microbiota; exercise ... See more keywords
Long term variation of serum levels of uremic toxins in patients treated by post-dilution high volume on-line hemodiafiltration in comparison to standard low-flux bicarbonate dialysis: results from the REDERT study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Nephrology"
DOI: 10.1007/s40620-017-0381-2
Abstract: Purpose of the studyLittle information have been provided till now regarding the effect of high volume HDF (hv-OL-HDF) in respect to standard bicarbonate dialysis (BHD) in medium-long term protein-bound toxins removal.ProceduresA randomised cross-over multicentre study… read more here.
Keywords: uremic toxins; volume; patients treated; high volume ... See more keywords
Silver nanoparticles embedded on mesoporous-silica modified reduced graphene-oxide nanosheets for SERS detection of uremic toxins and parathyroid hormone
Sign Up to like & getrecommendations! Published in 2020 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2020.146372
Abstract: Abstract Silver nanoparticles (AgNPs) were successfully immobilized onto mesoporous silica (MPS)-modified reduced graphene oxide (mrGO) nanosheets to form AgNPs@mrGO surface-enhanced Raman scattering (SERS)-active substrates for bio-detection. Using the highly porous structure of MPS with the… read more here.
Keywords: uremic toxins; silver nanoparticles; mesoporous silica; detection uremic ... See more keywords
Exploring binding characteristics and the related competition of different protein-bound uremic toxins.
Sign Up to like & getrecommendations! Published in 2017 at "Biochimie"
DOI: 10.1016/j.biochi.2017.05.010
Abstract: Little is known about potential differences in binding characteristics of protein-bound uremic toxins (PBUTs) in patients with chronic kidney disease (CKD) versus healthy controls. The question arises whether eventual differences are attributed to (i) the… read more here.
Keywords: uremic toxins; protein bound; binding characteristics; serum ... See more keywords
Toward Urease-free wearable artificial kidney: Widened interlayer spacing MoS2 nanosheets with highly effective adsorption for uremic toxins
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2022.135583
Abstract: The high incidence of kidney disease caused by various factors (such as COVID-19) has triggered an extreme desire for wearable artificial kidney (WAK). Nevertheless, the dialysate regeneration system in WAK presents a very low adsorption… read more here.
Keywords: uremic toxins; wdr mos2; wearable artificial; kidney ... See more keywords
Effect of uremic toxins on hippocampal cell damage: analysis in vitro and in rat model of chronic kidney disease
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e06221
Abstract: One third of the patients with chronic kidney disease (CKD) develop cognitive impairment, which is also an independent risk factor for mortality. However, the concise mechanism of cerebro-renal interaction has not been clarified. The present… read more here.
Keywords: uremic toxins; neuronal cells; kidney disease; chronic kidney ... See more keywords
Protein-bound uremic toxins (PBUTs) in chronic kidney disease (CKD) patients: Production pathway, challenges and recent advances in renal PBUTs clearance
Sign Up to like & getrecommendations! Published in 2021 at "NanoImpact"
DOI: 10.1016/j.impact.2021.100299
Abstract: Abstract Uremic toxins, a group of uremic retention solutes with high concentration which their accumulation on the body makes several biological problems, have recently gained a large interest. The importance of this issue more targets… read more here.
Keywords: bound uremic; protein bound; clearance; uremic toxins ... See more keywords
A rapid and sensitive method for simultaneous determination of eight protein-bound uremic toxins in human serum by UHPLC-MS/MS: application in assessing peritoneal dialysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113312
Abstract: A simple, rapid, reliable and sensitive ultra-high performance liquid chromatography tandem spectrometry (UHPLC-MS/MS) method was established for determination of eight serum protein-bound uremic toxins (hippuric acid, indoxyl sulfate, indole-3-acetic acid, kynurenic acid, L-kynurenine, melatonin, 3-carboxy-4-methyl-5-propyl-2-furanpropionic… read more here.
Keywords: protein bound; bound uremic; uremic toxins; method ... See more keywords
Accumulation of protein-bound uremic toxins: the kidney remains the leading culprit in the gut-liver-kidney axis.
Sign Up to like & getrecommendations! Published in 2020 at "Kidney international"
DOI: 10.1016/j.kint.2020.02.026
Abstract: Protein-bound uremic toxins (PBUTs) accumulate in chronic kidney disease (CKD) and are poorly removed by dialysis. Gryp et al. demonstrated that fecal bacteria from patients with CKD do not produce more PBUTs than do those from… read more here.
Keywords: protein bound; bound uremic; uremic toxins; liver kidney ... See more keywords