Activated prothrombin complex concentrates for direct oral anticoagulant-associated bleeding or urgent surgery: Hemostatic and thrombotic outcomes.
Sign Up to like & getrecommendations! Published in 2020 at "Thrombosis research"
DOI: 10.1016/j.thromres.2020.06.044
Abstract: INTRODUCTION Studies evaluating the use of activated prothrombin complex concentrates (aPCCs) for DOAC-associated bleeding are sparse. MATERIALS AND METHODS We conducted a retrospective study of patients receiving aPCC for DOAC-associated bleeding or for pre-operative optimization… read more here.
Keywords: urgent surgery; apcc; activated prothrombin; prothrombin complex ... See more keywords
Healthcare resource utilization in patients receiving idarucizumab for reversal of dabigatran anticoagulation due to major bleeding, urgent surgery, or procedural interventions: interim results from the RE-VERSE AD™ study
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DOI: 10.1080/13696998.2016.1273229
Abstract: Abstract Aims: Patients treated with anticoagulants may experience serious bleeding or require urgent surgery or intervention, and may benefit from rapid anticoagulant reversal. This exploratory analysis assessed healthcare resource utilization (HCRU) in patients treated with… read more here.
Keywords: reversal; surgery; healthcare resource; urgent surgery ... See more keywords
Prothrombin Complex Concentrate before Urgent Surgery in Patients Treated with Rivaroxaban and Apixaban
Sign Up to like & getrecommendations! Published in 2019 at "Acta Haematologica"
DOI: 10.1159/000502173
Abstract: Introduction: Patients treated with direct Xa inhibitors may require urgent surgery. Administration of prothrombin complex concentrate (PCC) in this setting is common; however, it is based on limited experience in healthy volunteers. Objective: To characterize… read more here.
Keywords: surgery; patients treated; urgent surgery; prothrombin complex ... See more keywords
Prothrombin Complex Concentrate Is Safe and Effective for Achieving Hemostasis in the Setting of Urgent Surgery for Patients Treated with Direct Xa Inhibitors
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DOI: 10.1182/blood-2018-99-117378
Abstract: Introduction: Patients treated with direct Xa inhibitors may require an urgent surgery. A reversal agent for Xa inhibitors was recently approved for major bleeding but not prior to urgent surgery. Administration of prothrombin complex concentrate… read more here.
Keywords: prior urgent; surgery; treated direct; direct inhibitors ... See more keywords
A monocentric retrospective analysis about the effects of COVID-19 pandemic on emergency general surgery consultations.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202206_29092
Abstract: OBJECTIVE The pandemic effects due to the coronavirus SARS-CoV-2 caused a health emergency. We decided to carry out a study with the aim to investigate the changes in patients' tendencies for admission to the emergency… read more here.
Keywords: emergency general; surgery; general surgery; hospitalization ... See more keywords
How I manage patients with anticoagulation-associated bleeding or urgent surgery.
Sign Up to like & getrecommendations! Published in 2018 at "Swiss medical weekly"
DOI: 10.4414/smw.2018.14598
Abstract: Antithrombotic treatment puts patients at risk of major bleeding. Fast and adequate response to anticoagulant-associated bleeding may not only stop the bleeding but prevent severe complications. However, practical treatment algorithms to guide physicians in emergency… read more here.
Keywords: surgery; bleeding urgent; reversal agents; manage patients ... See more keywords