Articles with "uridine derivatives" as a keyword



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5-(Halomethyl)uridine derivatives as potential antitumor radiosensitizers: A DFT study

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Published in 2018 at "Chemical Physics Letters"

DOI: 10.1016/j.cplett.2017.12.062

Abstract: Abstract Considering the fact that the efficiency of the uridine-5-methyl radical in producing cytotoxic DNA intrastrand cross-link lesions is greatly higher than that of the uridine-5-yl radical, the radiosensitizing action of 5-(halomethyl)uridines (5-XCH2U, X = F, Cl,… read more here.

Keywords: derivatives potential; antitumor radiosensitizers; uridine derivatives; halomethyl uridine ... See more keywords