Study of a 1,8-naphtylimide derivative as uridine diphosphate selective probe: Synthesis, optical properties and in vivo imaging application
Sign Up to like & getrecommendations! Published in 2017 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2017.04.006
Abstract: Abstract A 1, 8-naphtylimide-based probe 1 was developed for fluorescence sensing of uridine diphosphate (UDP). Probe 1 selectively recognized UDP in solvant system (DMSO-H 2 O) over other structurally similar nucleotides. Among all the tested… read more here.
Keywords: uridine diphosphate; study naphtylimide; probe; naphtylimide derivative ... See more keywords
Methylglyoxal augments uridine diphosphate-induced contraction via activation of p38 mitogen-activated protein kinase in rat carotid artery.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174155
Abstract: The methylglyoxal elicits diverse adverse effects on the body. Uridine diphosphate, an extracellular nucleotide, plays an important role as a signaling molecule controlling vascular tone. This study aimed to evaluate the relationship between methylglyoxal and… read more here.
Keywords: uridine diphosphate; induced contraction; methylglyoxal; diphosphate ... See more keywords
Uridine diphosphate glucuronosyltransferase 1A1
Sign Up to like & getrecommendations! Published in 2019 at "Xenobiotica"
DOI: 10.1080/00498254.2019.1617910
Abstract: Abstract The role that the phase-II reaction, glucuronidation, plays in the biotransformation of endo and xenobiotics is discussed with particular emphasis given to the UGT1A1 isoenzyme. This individual isoenzyme is responsible for both the mono… read more here.
Keywords: irinotecan belinostat; uridine diphosphate; glucuronidation; glucuronosyltransferase 1a1 ... See more keywords
Effects of common genetic variants of human uridine diphosphate glucuronosyltransferase subfamilies on irinotecan glucuronidation
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2022.2109229
Abstract: Abstract The adverse effects (diarrhea and neutropenia) of irinotecan (7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin) are associated with genetic variants of uridine diphosphate glucuronosyltransferase 1A subfamilies (UGT1As). UGT1As are enzymes that metabolize the active form of irinotecan, 7-ethyl-10 hydroxycamptothecin (SN-38),… read more here.
Keywords: genetic variants; adverse effects; glucuronidation; glucuronosyltransferase subfamilies ... See more keywords
Age‐related change of hepatic uridine diphosphate glucuronosyltransferase and sulfotransferase activities in male chickens and pigs
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Veterinary Pharmacology and Therapeutics"
DOI: 10.1111/jvp.12355
Abstract: The hepatic activities of uridine diphosphate glucuronosyltransferase (UGT) and sulfotransferase (SULT) of male Ross 708 broiler chickens at the age of 1, 7, 14, 28, and 56 days and male Camborough-29 pigs at the age of… read more here.
Keywords: sult; uridine diphosphate; hepatic ugt; age ... See more keywords
Regulation of uridine diphosphate-glucuronosyltransferase 2B15 expression during ovulation in the rat.
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine journal"
DOI: 10.1507/endocrj.ej16-0469
Abstract: Uridine diphosphate-glucuronosyltransferase 2B15 (UGT2B15) conjugates 5α-androstane-3α, 17β-diol (3α-diol) to 3α-diol glucuronide (3α-diol G) in steroid target tissues. The present study investigated the regulation of UGT2B15 expression during the ovulatory process in the rat. Real-time PCR… read more here.
Keywords: uridine diphosphate; preovulatory follicles; diphosphate glucuronosyltransferase; ugt2b15 expression ... See more keywords
Genomic-Wide Identification and Characterization of the Uridine Diphosphate Glycosyltransferase Family in Eucommia ulmoides Oliver
Sign Up to like & getrecommendations! Published in 2021 at "Plants"
DOI: 10.3390/plants10091934
Abstract: Eucommia ulmoides Oliver is a woody plant with great economic and medicinal value. Its dried bark has a long history of use as a traditional medicinal material in East Asia, which led to many glycosides,… read more here.
Keywords: uridine diphosphate; eucommia ulmoides; genomic wide; diphosphate ... See more keywords