A Mechanism for microRNA Arm Switching Regulated by Uridylation.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular cell"
DOI: 10.1016/j.molcel.2020.04.030
Abstract: Strand selection is a critical step in microRNA (miRNA) biogenesis. Although the dominant strand may change depending on cellular contexts, the molecular mechanism and physiological significance of such alternative strand selection (or "arm switching") remain… read more here.
Keywords: strand; arm switching; mechanism; uridylation ... See more keywords
Uridylation and the SKI complex orchestrate the Calvin cycle of photosynthesis through RNA surveillance of TKL1 in Arabidopsis
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2205842119
Abstract: Significance RNA uridylation is a conserved and widespread posttranscriptional modification that impacts a multitude of RNA metabolic processes. In Arabidopsis, HEN1 SUPPRESSOR 1 (HESO1) and UTP: RNA URIDYLYLTRANSFERASE (URT1) catalyze uridylation of both small RNA… read more here.
Keywords: tkl1; rna; calvin cycle; uridylation ... See more keywords
Pervasive mRNA uridylation in fission yeast is catalysed by both Cid1 and Cid16 terminal uridyltransferases
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1101/2022.10.04.510797
Abstract: Messenger RNA uridylation is pervasive and conserved among eukaryotes, but the consequences of this modification for mRNA fate are still under debate. Utilising a simple model organism to study uridylation may facilitate efforts to understand… read more here.
Keywords: cid1 cid16; uridylation; fission yeast; uridylation fission ... See more keywords