Urinary cell mRNA profiling of kidney allograft recipients: Development of a portable protocol for noninvasive diagnosis of T cell mediated rejection and BK virus nephropathy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of immunological methods"
DOI: 10.1101/2022.09.15.22279980
Abstract: Background: We developed urinary cell mRNA profiling for the noninvasive diagnosis of acute T cell mediated rejection (TCMR) and BK virus nephropathy (BKVN), two significant post-transplant complications. Our profiling protocol for the multicenter Clinical Trial… read more here.
Keywords: allograft recipients; kidney allograft; cell; urinary cell ... See more keywords
Fragmentomics of urinary cell-free DNA in nuclease knockout mouse models
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1010262
Abstract: Urinary cell-free DNA (ucfDNA) is a potential biomarker for bladder cancer detection. However, the biological characteristics of ucfDNA are not well understood. We explored the roles of deoxyribonuclease 1 (DNASE1) and deoxyribonuclease 1-like 3 (DNASE1L3)… read more here.
Keywords: dna; cell free; urinary cell; free dna ... See more keywords
Toward urinary cell-free DNA-based treatment of urothelial carcinoma: a narrative review.
Sign Up to like & getrecommendations! Published in 2021 at "Translational andrology and urology"
DOI: 10.21037/tau-20-1259
Abstract: Liquid biopsy technique targeting urinary cell-free DNA (cfDNA) is getting a lot of attention to overcome limitations of the present treatment strategy for urothelial carcinoma, including urothelial bladder carcinoma (UBC) and upper tract urothelial carcinoma… read more here.
Keywords: cell free; carcinoma; urothelial carcinoma; free dna ... See more keywords