A preliminary origin‐tracking study of different densities urinary exosomes
Sign Up to like & getrecommendations! Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700388
Abstract: Based on density differences of different subpopulations of exosomes, two kinds of micro‐vesicles with different densities were captured from urine by a modified sucrose density gradient ultracentrifuge separation method. Verified by transmission electron microscope (TEM)… read more here.
Keywords: different densities; tracking study; origin tracking; urinary exosomes ... See more keywords
In-Depth Compositional and Structural Characterization of N-Glycans Derived from Human Urinary Exosomes.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b02620
Abstract: The study of exosomes has become increasingly popular due to their potentially important biological roles. Urine can be used as an effective source of exosomes for noninvasive investigations into the pathophysiological states of the genitourinary… read more here.
Keywords: mass spectrometry; depth compositional; urinary exosomes; compositional structural ... See more keywords
Ultrasensitive and Reversible Nanoplatform of Urinary Exosomes for Prostate Cancer Diagnosis.
Sign Up to like & getrecommendations! Published in 2019 at "ACS sensors"
DOI: 10.1021/acssensors.9b00621
Abstract: Prostate cancer cell-derived exosomes in urine have been extensively studied recently and regarded as novel biomarkers for cancer diagnosis and prognosis, which presents wide prospects in clinical applications. Sensitive detection and specific capture methods are… read more here.
Keywords: detection; urinary exosomes; prostate cancer; cancer ... See more keywords
Urinary Exosomes Contain MicroRNAs Capable of Paracrine Modulation of Tubular Transporters in Kidney
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40601
Abstract: Exosomes derived from all nephron segments are present in human urine, where their functionality is incompletely understood. Most studies have focused on biomarker discovery rather than exosome function. Through sequencing we identified the miRNA repertoire… read more here.
Keywords: capable paracrine; paracrine modulation; urinary exosomes; contain micrornas ... See more keywords
Urinary exosomes derived circRNAs as biomarkers for chronic renal fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Medicine"
DOI: 10.1080/07853890.2022.2098374
Abstract: Abstract Background Chronic renal disease (CKD) is a common and irreversible loss of renal function. Renal fibrosis reflected the degree of renal dysfunction. However, the current biomarkers only characterize the renal function instead of indicating… read more here.
Keywords: renal fibrosis; hsa circ; urinary exosomes; circ 0036649 ... See more keywords
The urinary exosomes derived from premature infants attenuate cisplatin-induced acute kidney injury in mice via microRNA-30a-5p/ mitogen-activated protein kinase 8 (MAPK8)
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2021686
Abstract: ABSTRACT Acute kidney injury (AKI) is a susceptible factor for chronic kidney disease (CKD). There is still a lack of effective prevention methods in clinical practice. This study investigated the protective effect of the urinary… read more here.
Keywords: acute kidney; kidney injury; urinary exosomes; premature infants ... See more keywords
Urinary Exosomes: A Promising Biomarker for Disease Diagnosis.
Sign Up to like & getrecommendations! Published in 2022 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac087
Abstract: Exosomes are nanoscale vesicles derived from endocytosis, formed by fusion of multivesicular bodies with membranes and secreted into the extracellular matrix or body fluids. Many studies have shown that exosomes can be present in a… read more here.
Keywords: exosomes promising; disease; urinary exosomes; promising biomarker ... See more keywords
THE ROLE OF URINARY EXOSOMAL SODIUM CHLORIDE COTRANSPORTER IN SUBTYPING PRIMARY ALDOSTERONISM
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837492.67542.80
Abstract: Objective: Adrenal venous sampling (AVS) is recognized as the gold standard for subtyping primary aldosteronism (PA), but its invasive nature and technical challenges limit its availability. A recent study reported that sodium chloride cotransporter (NCC)… read more here.
Keywords: sodium chloride; subtyping primary; chloride cotransporter; group ... See more keywords
Expression of Small Non-coding RNAs in Urinary Exosomes Classifies Prostate Cancer into Indolent and Aggressive Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000001020
Abstract: PURPOSE This is the first report of the development and performance of a platform that interrogates small non-coding RNAs (sncRNA) isolated from urinary exosomes (the miR Sentinel™ Tests): the Sentinel™ PCa Test, that classifies patients… read more here.
Keywords: small non; test; cancer; urinary exosomes ... See more keywords
Urinary exosomes reveal protein signatures in hypertensive patients with albuminuria
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17787
Abstract: Albuminuria is an indicator of cardiovascular risk and renal damage in hypertensive individuals. Chronic renin–angiotensin system (RAS) suppression facilitates blood pressure control and prevents development of new-onset-albuminuria. A significant number of patients, however, develop albuminuria… read more here.
Keywords: exosomes reveal; reveal protein; protein signatures; urinary exosomes ... See more keywords
Cancer exosomes in urine: a promising biomarker source
Sign Up to like & getrecommendations! Published in 2017 at "Translational cancer research"
DOI: 10.21037/16436
Abstract: In face of innovative therapeutic strategies for cancer diagnosis and treatment, and of the elusiveness of renal and urinary tract tumors, the identification of novel biomarkers for diagnosis, prognosis, selection and monitoring of therapies is… read more here.
Keywords: exosomes urine; urinary exosomes; promising biomarker; cancer exosomes ... See more keywords