EIF2S1 in Urinary Extracellular Vesicles as a Novel Diagnostic Marker for Bladder Cancer
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Medicine"
DOI: 10.1002/cam4.70964
Abstract: Urinary extracellular vesicles (uEVs), directly secreted from bladder cancer (BCa) cells, harbor potential for biomarker discovery. read more here.
Keywords: extracellular vesicles; cancer; urinary extracellular; eif2s1 urinary ... See more keywords
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12093
Abstract: Abstract Urine is commonly used for clinical diagnosis and biomedical research. The discovery of extracellular vesicles (EV) in urine opened a new fastâgrowing scientific field. In the last decade urinary extracellular vesicles (uEVs) were shown… read more here.
Keywords: extracellular vesicles; research; urinary extracellular; urine task ... See more keywords
Defining Biological Variability, Analytical Precision and Quantitative Biophysiochemical Characterization of Human Urinary Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70087
Abstract: ABSTRACT The magnitude of combined analytical errors of urinary extracellular vesicle (uEV) preparation and measurement techniques (CVA) has not been thoroughly investigated to determine whether it exceeds biological variations. We utilized technical replicates of human… read more here.
Keywords: extracellular vesicles; urinary extracellular; precision; variability ... See more keywords
PruEV-AI: a Simple Approach Combines Urinary Extracellular Vesicle Isolation with AI-Assisted Analysis for Prostate Cancer Diagnosis.
Sign Up to like & getrecommendations! Published in 2025 at "Small methods"
DOI: 10.1002/smtd.202500659
Abstract: Urinary extracellular vesicles (uEVs) are a promising source of prostate-derived biomarkers for non-invasive prostate cancer (PCa) diagnosis. However, conventional uEV isolation methods and single-marker assays often lack efficiency and diagnostic accuracy. Here, PruEV-AI is introduced,… read more here.
Keywords: diagnosis; prostate; urinary extracellular; prostate cancer ... See more keywords
Urinary Extracellular Vesicle Protein Profiling and Endogenous Lithium Clearance Support Excessive Renal Sodium Wasting and Water Reabsorption in Thiazide-Induced Hyponatremia
Sign Up to like & getrecommendations! Published in 2019 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2018.09.011
Abstract: Introduction Thiazide diuretics are among the most widely used antihypertensive medications worldwide. Thiazide-induced hyponatremia (TIH) is 1 of their most clinically significant adverse effects. A priori TIH must result from excessive saliuresis and/or water reabsorption.… read more here.
Keywords: endogenous lithium; water; urinary extracellular; water reabsorption ... See more keywords
Multiplex Biomarker Screening Assay for Urinary Extracellular Vesicles Study: A Targeted Label-Free Proteomic Approach
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-33280-7
Abstract: The recent advance in targeted label-free proteomics, SWATH-MS, can provide consistent protein detection and reproducible protein quantitation, which is a considerable advantage for biomarker study of urinary extracellular vesicles. We developed a SWATH-MS workflow with… read more here.
Keywords: extracellular vesicles; biomarker; urinary extracellular; label free ... See more keywords
Urinary extracellular vesicles: does cargo reflect tissue?
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000822
Abstract: Purpose of review To review recent developments in urinary extracellular vesicles (uEVs) to study kidney physiology and disease. Recent findings Proteomic analysis in rats showed significant correlations between kidney and uEV protein abundances. Consistent with… read more here.
Keywords: extracellular vesicles; kidney; urinary extracellular; physiology ... See more keywords
Dysregulated Urinary Extracellular Vesicle Small RNAs in Diabetic Nephropathy: Implications for Diagnosis and Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvae114
Abstract: Abstract Background Diabetic nephropathy (DN) represents a major chronic kidney disorder and a leading cause of end-stage renal disease (ESRD). Small RNAs have been showing great promise as diagnostic markers as well as drug targets.… read more here.
Keywords: urinary extracellular; small rnas; dysregulated urinary; extracellular vesicle ... See more keywords
Large-Scale Proteomic Assessment of Urinary Extracellular Vesicles Highlights Their Reliability in Reflecting Protein Changes in the Kidney.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2020071035
Abstract: Background: Urinary extracellular vesicles (uEVs) are secreted into urine by cells from the kidneys and urinary tract. Although changes in uEV proteins are used for quantitative assessment of protein levels in the kidney or biomarker… read more here.
Keywords: changes kidney; large scale; extracellular vesicles; urinary extracellular ... See more keywords
Targeted proteomics in urinary extracellular vesicles identifies biomarkers for diagnosis and prognosis of prostate cancer
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.13634
Abstract: Rapid and reliable diagnosis of prostate cancer (PCa) is highly desirable as current used methods lack specificity. In addition, identification of PCa biomarkers that can classify patients into high- and low-risk groups for disease progression… read more here.
Keywords: extracellular vesicles; urinary extracellular; prostate cancer; targeted proteomics ... See more keywords
Urinary extracellular vesicles carry multiple activators and regulators of coagulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.967482
Abstract: Cells shape their extracellular milieu by secreting intracellular products into the environment including extracellular vesicles which are lipid-bilayer limited membrane particles. These vesicles carry out a range of functions, including regulation of coagulation, via multiple… read more here.
Keywords: vesicles carry; coagulation; extracellular vesicles; carry multiple ... See more keywords