The Relationship between Increases in Morning Spot Urinary Glucose Excretion and Decreases in HbA1C in Patients with Type 2 Diabetes After Taking an SGLT2 Inhibitor: A Retrospective, Longitudinal Study
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DOI: 10.1007/s13300-017-0248-5
Abstract: AbstractIntroduction Sodium glucose co-transporter 2 (SGLT2) inhibitors increase urinary glucose excretion (UGE) by reducing the renal threshold for glucose excretion, which results in decreased serum glucose concentrations in patients with type 2 diabetes mellitus (T2D).… read more here.
Keywords: sglt2 inhibitor; urinary glucose; morning spot; morning ... See more keywords
Using a Mathematical Modeling To Simulate Pharmacokinetics and Urinary Glucose Excretion of Luseogliflozin and Explore the Role of SGLT1/2 in Renal Glucose Reabsorption
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DOI: 10.1021/acsomega.2c06483
Abstract: (1) Purpose: To develop a mathematical model combining physiologically based pharmacokinetic and urinary glucose excretion (PBPK-UGE) to simultaneously predict pharmacokinetic (PK) and UGE changes of luseogliflozin (LUS) as well as to explore the role of… read more here.
Keywords: urinary glucose; reabsorption; glucose; explore role ... See more keywords
2354-PUB: Estimating Improvement of TGF Mechanism from Changes of Urinary Glucose and Sodium Excretion by SGLT2 Inhibitors
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DOI: 10.2337/db19-2354-pub
Abstract: The renoprotective effect through the tubuloglomerular feedback mechanism (TGF) with the Sodium-glucose cotransporter2 inhibitor (SG) attracts attention. We investigated whether the improvement of TGF can be estimated from urinary glucose (UG) and urinary sodium (UNa)… read more here.
Keywords: improvement tgf; urinary glucose; sodium; excretion ... See more keywords
Morning Spot Urine Glucose-to-Creatinine Ratios Predict Overnight Urinary Glucose Excretion in Patients With Type 2 Diabetes
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DOI: 10.3343/alm.2017.37.1.9
Abstract: Background With the advent of sodium glucose co-transporter 2 inhibitors to control glucose and treat diabetes, laboratory data aided by either timed or spot glucose levels in the urine could be used as an alternative… read more here.
Keywords: overnight urinary; spot; urine; morning spot ... See more keywords