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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8579-1_15
Abstract: A method was developed for the analysis of stimulant drugs, opiates, synthetic opiates, PCP, and benzodiazepines in wastewater samples using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS). A total of 33 compounds (stimulant-type drugs…
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Keywords:
metabolite;
primary urinary;
opiates pcp;
opiates synthetic ... See more keywords
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Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c02041
Abstract: The urine metabolome constitutes a rich source of functional information reflecting physiological states that are influenced by distinct conditions and biological stresses, such as responses to drug treatments or disease manifestations. Although global liquid chromatography-mass…
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Keywords:
annotation integrated;
expanding urinary;
similarity;
annotation ... See more keywords
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Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c06334
Abstract: The present study showed that oral administration of tangeretin (TAN) in mice resulted in the production of 4'-demethyltangeretin (4DT) as a major urinary metabolite. The anti-inflammatory efficacy of TAN and 4DT was determined in RAW…
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Keywords:
anti inflammatory;
demethyltangeretin;
major urinary;
tangeretin ... See more keywords
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Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03983
Abstract: A chemical synthesis of the major human metabolite of prostaglandin D2, tricyclic-PGDM, is described. The synthetic route starts from iodocyclopentenone 1 (available from cyclopentadiene in 6 steps) and requires 13 synthetic transformations. The synthetic route…
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Keywords:
metabolite prostaglandin;
synthesis human;
human urinary;
metabolite ... See more keywords