Articles with "urinary metabolite" as a keyword



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LC-MS-MS Method Development and Analysis of Stimulants, Opiates, Synthetic Opiates, PCP, and Benzodiazepines in Wastewater. Preponderance of these Drugs During Football Games.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-8579-1_15

Abstract: A method was developed for the analysis of stimulant drugs, opiates, synthetic opiates, PCP, and benzodiazepines in wastewater samples using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS). A total of 33 compounds (stimulant-type drugs… read more here.

Keywords: metabolite; primary urinary; opiates pcp; opiates synthetic ... See more keywords
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Expanding Urinary Metabolite Annotation through Integrated Mass Spectral Similarity Networking.

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Published in 2021 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.1c02041

Abstract: The urine metabolome constitutes a rich source of functional information reflecting physiological states that are influenced by distinct conditions and biological stresses, such as responses to drug treatments or disease manifestations. Although global liquid chromatography-mass… read more here.

Keywords: annotation integrated; expanding urinary; similarity; annotation ... See more keywords

Identification of 4'-Demethyltangeretin as a Major Urinary Metabolite of Tangeretin in Mice and Its Anti-inflammatory Activities.

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Published in 2021 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.0c06334

Abstract: The present study showed that oral administration of tangeretin (TAN) in mice resulted in the production of 4'-demethyltangeretin (4DT) as a major urinary metabolite. The anti-inflammatory efficacy of TAN and 4DT was determined in RAW… read more here.

Keywords: anti inflammatory; demethyltangeretin; major urinary; tangeretin ... See more keywords
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Synthesis of a Human Urinary Metabolite of Prostaglandin D2.

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Published in 2019 at "Organic letters"

DOI: 10.1021/acs.orglett.9b03983

Abstract: A chemical synthesis of the major human metabolite of prostaglandin D2, tricyclic-PGDM, is described. The synthetic route starts from iodocyclopentenone 1 (available from cyclopentadiene in 6 steps) and requires 13 synthetic transformations. The synthetic route… read more here.

Keywords: metabolite prostaglandin; synthesis human; human urinary; metabolite ... See more keywords