An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluria
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DOI: 10.15252/msb.202110539
Abstract: Enteric hyperoxaluria (EH) is a metabolic disease caused by excessive absorption of dietary oxalate leading to the formation of chronic kidney stones and kidney failure. There are no approved pharmaceutical treatments for EH. SYNB8802 is… read more here.
Keywords: bacterial therapeutic; oxalate excretion; urinary oxalate; therapeutic lowers ... See more keywords