Inducing differentiation of human urine‐derived stem cells into hepatocyte‐like cells by coculturing with human hepatocyte L02 cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29301
Abstract: To investigate the possibility of inducing differentiation of human urine‐derived stem cells (hUSCs) into hepatocyte‐like cells by coculturing with human hepatocyte L02 cells in vitro. read more here.
Keywords: human urine; inducing differentiation; differentiation human; derived stem ... See more keywords
Laminin and Platelet-Derived Growth Factor-BB Promote Neuronal Differentiation of Human Urine-Derived Stem Cells
Sign Up to like & getrecommendations! Published in 2017 at "Tissue Engineering and Regenerative Medicine"
DOI: 10.1007/s13770-017-0102-x
Abstract: Abstract Urine-derived stem cells (USCs) are considered as a promising cell source capable of neuronal differentiation. In addition, specific growth factors and extracellular matrix are essential for enhancing their neuronal differentiation efficiency. In this study,… read more here.
Keywords: differentiation; laminin; stem; growth ... See more keywords
Differentiation of human urine-derived stem cells into interstitial cells of Cajal-like cells by exogenous gene modification: A preliminary study.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.121
Abstract: Human urine-derived stem cells (hUSCs) show multipotential differentiation ability and can differentiate into mesodermal cell lineages. Interstitial cells of Cajal-like cells (ICC-LCs) are crucial for the pace-making function of spontaneous contraction in the bladder. However,… read more here.
Keywords: human urine; derived stem; icc lcs; differentiation ... See more keywords
Highly sensitive screening of antisense sequences for different types of DMD mutations in patients' urine-derived cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2021.117337
Abstract: Exon skipping using short antisense oligonucleotides (AONs) is a promising treatment for Duchenne muscular dystrophy (DMD). Several exon-skipping drugs, including viltolarsen (NS-065/NCNP-01), have been approved worldwide. Immortalized human skeletal muscle cell lines, such as rhabdomyosarcoma… read more here.
Keywords: rhabdomyosarcoma cells; highly sensitive; derived cells; exon skipping ... See more keywords
Generation of human iPSCs from urine derived cells of a non-affected control subject.
Sign Up to like & getrecommendations! Published in 2017 at "Stem cell research"
DOI: 10.1016/j.scr.2016.12.008
Abstract: We have generated a human induced pluripotent stem cell (iPSC) line under feeder-free culture conditions using the urine derived cells (UCs) collected from non-affected control subjects to use as a comparison group for the iPSC… read more here.
Keywords: affected control; generation human; non affected; derived cells ... See more keywords
Chemical cocktails enable hepatic reprogramming of human urine-derived cells with a single transcription factor
Sign Up to like & getrecommendations! Published in 2018 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-018-0170-z
Abstract: Human liver or hepatocyte transplantation is limited by a severe shortage of donor organs. Direct reprogramming of other adult cells into hepatic cells may offer a solution to this problem. In a previous study, we… read more here.
Keywords: human urine; like cells; transcription factor; hepatocyte ... See more keywords
Urine-derived cells: a promising diagnostic tool in Fabry disease patients
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29240-w
Abstract: Fabry disease is a lysosomal storage disorder resulting from impaired alpha-galactosidase A (α-Gal A) enzyme activity due to mutations in the GLA gene. Currently, powerful diagnostic tools and in vivo research models to study Fabry… read more here.
Keywords: disease patients; fabry disease; disease; derived cells ... See more keywords
Differentiation of Urine-Derived Induced Pluripotent Stem Cells to Neurons, Astrocytes, and Microvascular Endothelial Cells from a Diabetic Patient.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular reprogramming"
DOI: 10.1089/cell.2019.0088
Abstract: Complications of central nervous system in type 2 diabetes mellitus (T2DM) often lead to cognitive impairment and seriously affect the quality of life. However, there is no individualized disease model. Urine-derived stem cells can be… read more here.
Keywords: microvascular endothelial; pluripotent stem; induced pluripotent; stem cells ... See more keywords
Intratunical injection of human urine‐derived stem cells derived exosomes prevents fibrosis and improves erectile function in a rat model of Peyronie's disease
Sign Up to like & getrecommendations! Published in 2020 at "Andrologia"
DOI: 10.1111/and.13831
Abstract: We aimed to evaluate the effects of intratunical injection of exosomes derived from human urine‐derived stem cells (USC‐exo) on plaque formation and erectile function in a transforming growth factor‐β1 (TGF‐β1) induced Peyronie's disease (PD) rat… read more here.
Keywords: human urine; group; intratunical injection; injection ... See more keywords
Extracellular vesicles from human urine‐derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration
Sign Up to like & getrecommendations! Published in 2022 at "Andrology"
DOI: 10.1111/andr.13293
Abstract: The high prevalence of erectile dysfunction (ED) in patients with type 2 diabetes mellitus (DM2) is a challenging clinical problem. Researches on extracellular vesicles from urine‐derived stem cells (USC‐EVs) have shown that they have significant… read more here.
Keywords: derived stem; extracellular vesicles; erectile dysfunction; hyaluronic acid ... See more keywords
Isolation and Characterization of Multipotent Canine Urine-Derived Stem Cells
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells International"
DOI: 10.1155/2020/8894449
Abstract: Current cell-based therapies on musculoskeletal tissue regeneration were mostly determined in rodent models. However, a direct translation of those promising cell-based therapies to humans exists a significant hurdle. For solving this problem, canine has been… read more here.
Keywords: stem cells; canine; urine derived; isolation characterization ... See more keywords