Expression of urokinase-type plasminogen activator system in non-metastatic prostate cancer
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Urology"
DOI: 10.1007/s00345-019-03038-5
Abstract: To investigate the prognostic role of expression of urokinase-type plasminogen activator system members, such as urokinase-type activator (uPA), uPA-receptor (uPAR), and plasminogen activator inhibitor-1 (PAI-1), in patients treated with radical prostatectomy (RP) for prostate cancer… read more here.
Keywords: system; pai; activator; urokinase type ... See more keywords
Novel Biomarkers: Soluble Urokinase-Type Plasminogen Activator Receptor and Procalcitonin- and Histological Chorioamnionitis after Preterm Premature Rupture of Membranes
Sign Up to like & getrecommendations! Published in 2024 at "Reproductive Sciences"
DOI: 10.1007/s43032-024-01678-6
Abstract: Fetal inflammatory response syndrome or infection after preterm premature rupture of membranes (PPROM) increases neonatal morbidity in preterm deliveries. Biochemical markers from the amniotic fluid (AF) have been used to evaluate possible intra-amniotic infection during… read more here.
Keywords: urokinase type; rupture membranes; soluble urokinase; chorioamnionitis ... See more keywords
Cell Cycle Biomarkers and Soluble Urokinase-Type Plasminogen Activator Receptor for the Prediction of Sepsis-Induced Acute Kidney Injury Requiring Renal Replacement Therapy: A Prospective, Exploratory Study
Sign Up to like & getrecommendations! Published in 2019 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000004042
Abstract: Supplemental Digital Content is available in the text. read more here.
Keywords: cycle biomarkers; urokinase type; biomarkers soluble; type plasminogen ... See more keywords
Plasma Level of Soluble Urokinase-type Plasminogen Activator Receptor Predicts the Severity of Acute Alcohol Pancreatitis
Sign Up to like & getrecommendations! Published in 2017 at "Pancreas"
DOI: 10.1097/mpa.0000000000000730
Abstract: Objectives Systemic levels of soluble urokinase-type plasminogen activator receptor (suPAR) are increased in various inflammatory and infectious diseases. We investigated the activation and prognostic value of plasma suPAR (P-suPAR) in patients experiencing their first acute… read more here.
Keywords: pancreatitis; type plasminogen; urokinase type; supar ... See more keywords
Prognostic value of soluble urokinase‐type plasminogen activator receptor in coronary artery disease: A meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.13867
Abstract: A potential inflammatory biomarker, soluble urokinase‐type plasminogen activator receptor (suPAR) has been utilized to assist the prognostic assessment of coronary artery disease (CAD) patients; however, outcomes have been inconsistent. The prognostic relevance of suPAR as… read more here.
Keywords: soluble urokinase; activator receptor; plasminogen activator; type plasminogen ... See more keywords
What is the Role of Soluble Urokinase-Type Plasminogen Activator in Renal Disease?
Sign Up to like & getrecommendations! Published in 2018 at "Nephron"
DOI: 10.1159/000490118
Abstract: Context: Soluble urokinase-type plasminogen activator (suPAR) is an inflammatory signal with pleiotropic biological effects depending on context and post-translational modifications. Recently, [Hayek, et al: Nat Med 2017; 23: 945–953] it has been found that there… read more here.
Keywords: type plasminogen; renal disease; urokinase type; disease ... See more keywords
The cAMP-ERK1/2 signaling pathway regulates urokinase-type plasminogen activator-induced bovine granulosa cell proliferation.
Sign Up to like & getrecommendations! Published in 2020 at "Reproduction"
DOI: 10.1530/rep-20-0165
Abstract: Although urokinase-type plasminogen activator (PLAU) and urokinase-type plasminogen activator receptor (PLAUR) have been reported to play key roles in ovarian function, their precise contribution to mammalian follicular development remains unclear. In this study, we firstly… read more here.
Keywords: type plasminogen; urokinase type; plau plaur; proliferation ... See more keywords
Soluble Urokinase-type Plasminogen Activator Receptor Predicts All-cause 5-Year Mortality in Ischemic Stroke and TIA.
Sign Up to like & getrecommendations! Published in 2017 at "In vivo"
DOI: 10.21873/invivo.11070
Abstract: AIM We evaluated soluble urokinase-type plasminogen activator receptor (suPAR) levels in different stroke subtypes and assessed their prognostic value regarding 5-year outcomes. MATERIALS AND METHODS The study included 117 stroke patients (81 males; mean=age 61±11… read more here.
Keywords: type plasminogen; urokinase type; year; mortality ... See more keywords
Urokinase-Type Plasminogen Activator Receptor (uPAR) in Inflammation and Disease: A Unique Inflammatory Pathway Activator
Sign Up to like & getrecommendations! Published in 2024 at "Biomedicines"
DOI: 10.3390/biomedicines12061167
Abstract: The urokinase-type plasminogen activator receptor (uPAR) is a unique protease binding receptor, now recognized as a key regulator of inflammation. Initially, uPA/uPAR was considered thrombolytic (clot-dissolving); however, recent studies have demonstrated its predominant immunomodulatory functions… read more here.
Keywords: receptor; urokinase type; activator; inflammation ... See more keywords
The Urokinase-Type Plasminogen Activator Receptor (uPAR) as a Mediator of Physiological and Pathological Processes: Potential Therapeutic Strategies
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DOI: 10.3390/cancers17203309
Abstract: Simple Summary uPAR (PLAUR) is a GPI-anchored receptor that concentrates pericellular proteolysis and couples it to cell migration and invasion via urokinase (uPA), vitronectin, integrins and the epidermal growth factor receptor (EGFR). These complexes activate… read more here.
Keywords: receptor; urokinase type; activator receptor; plasminogen activator ... See more keywords
Association between Serum Soluble Urokinase-Type Plasminogen Activator Receptor Level and Arterial Stiffness in Chronic Hemodialysis Patients
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm13030470
Abstract: Cardiovascular diseases (CVDs) remain a significant cause of death in hemodialysis (HD) patients. To explore their associations, we examine the role of soluble urokinase-type plasminogen activator receptor (suPAR) in arterial stiffness in chronic HD patients.… read more here.
Keywords: soluble urokinase; stiffness; hemodialysis patients; stiffness chronic ... See more keywords