Pre-operative and post-operative estimated glomerular filtration rate in Japanese patients with urological malignancies
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-017-1509-3
Abstract: BackgroundThe suitable methods evaluating glomerular filtration rate (GFR) have not been established in patients undergoing radical nephrectomy (RN) or radical nephroureterectomy (RNU) due to urological malignancies in Japan as well as worldwide.MethodsWe examined the relationship… read more here.
Keywords: urological malignancies; filtration rate; pre operative; glomerular filtration ... See more keywords
Patient-derived xenografts as in vivo models for research in urological malignancies
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Urology"
DOI: 10.1038/nrurol.2017.19
Abstract: Lack of appropriate models that recapitulate the complexity and heterogeneity of urological tumours precludes most of the preclinical reagents that target urological tumours from receiving regulatory approval. Patient-derived xenograft (PDX) models are characterized by direct… read more here.
Keywords: urological malignancies; research; pdx models; derived xenografts ... See more keywords
Current status and future prospects of antibody–drug conjugates in urological malignancies
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Urology"
DOI: 10.1111/iju.14925
Abstract: Antibody‐drug conjugates represent a promising new treatment option that uses the targeting ability of an antibody to deliver cytotoxic drugs directly to tumors. Antibody‐drug conjugates provide the opportunity to deliver drugs to antigen‐expressing cancer cells… read more here.
Keywords: drug conjugates; conjugates urological; urological malignancies; drug ... See more keywords
Establishment and Evaluation of Dual HDAC/BET Inhibitors as Therapeutic Options for Germ Cell Tumors and Other Urological Malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-22-0207
Abstract: Abstract Urological malignancies represent major challenges for clinicians, with annually rising incidences. In addition, cisplatin treatment induced long-term toxicities and the development of therapy resistance emphasize the need for novel therapeutics. In this study, we… read more here.
Keywords: cell; urological malignancies; bet inhibitors; hdac bet ... See more keywords
Sentinel Lymph Node Techniques in Urologic Oncology: Current Knowledge and Application
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DOI: 10.3390/cancers15092495
Abstract: Simple Summary Lymph node (LN) metastases are a significant concern in urological malignancies. However, current imaging techniques do not reliably detect micrometastases; thus, lymph node dissection (LND) remains the gold standard. Nevertheless, there is no… read more here.
Keywords: oncology; sentinel lymph; urological malignancies; lymph node ... See more keywords
Recurrent hypercalcaemia in a patient with dual urological malignancies: A rare life-threatening entity
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Anaesthesia"
DOI: 10.4103/ija.ija_811_21
Abstract: A 68-year-old male of the American Society of Anesthesiologists (ASA) physical status I, presented with biopsy-proven moderately differentiated squamous cell carcinoma of the penis and lower urinary tract symptoms. After complete metastatic workup, he was… read more here.
Keywords: dual urological; serum; hypercalcaemia patient; recurrent hypercalcaemia ... See more keywords