Phylogenetic Classification, Biofilm-Forming Capacity, Virulence Factors, and Antimicrobial Resistance in Uropathogenic Escherichia coli (UPEC).
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DOI: 10.1007/s00284-020-02173-2
Abstract: Uropathogenic Escherichia coli (UPEC) is the main cause of urinary tract infections; in recent years, its importance as a pathogen has increased due to the emergence of hypervirulent and multiresistant strains. In this study, 190… read more here.
Keywords: coli upec; escherichia coli; virulence; uropathogenic escherichia ... See more keywords
5-(3′,4′-Dihydroxyphenyl)-γ-valerolactone and its sulphate conjugates, representative circulating metabolites of flavan-3-ols, exhibit anti-adhesive activity against uropathogenic Escherichia coli in bladder epithelial cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2016.12.035
Abstract: Abstract Urinary tract infections (UTI) are mostly caused by uropathogenic Escherichia coli (UPEC). Cranberry-based products have shown preventive effects against UTI, and this has been partially attributed to their A-type proanthocyanidin content. However, recent evidence… read more here.
Keywords: bladder epithelial; epithelial cells; sulphate; escherichia coli ... See more keywords
Distribution of extended-spectrum β-lactam, quinolone and carbapenem resistance genes, and genetic diversity among uropathogenic Escherichia coli isolates in Tehran, Iran.
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DOI: 10.1016/j.jgar.2018.03.006
Abstract: OBJECTIVES Antimicrobial resistance among uropathogenic Escherichia coli (UPEC) is increasing. The aim of this study was to evaluate antimicrobial resistance in UPEC isolates and its correlation with virulence factors. METHODS A total of 120 E.… read more here.
Keywords: uropathogenic escherichia; among uropathogenic; coli; antimicrobial resistance ... See more keywords
The insect antimicrobial peptide cecropin A disrupts uropathogenic Escherichia coli biofilms
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DOI: 10.1038/s41522-020-0116-3
Abstract: Current antibiotics cannot eradicate uropathogenic Escherichia coli (UPEC) biofilms, leading to recurrent urinary tract infections. Here, we show that the insect antimicrobial peptide cecropin A (CecA) can destroy planktonic and sessile biofilm-forming UPEC cells, either… read more here.
Keywords: insect antimicrobial; escherichia coli; uropathogenic escherichia; antimicrobial peptide ... See more keywords
Differential interleukin-1β induction by uropathogenic Escherichia coli correlates with its phylotype and serum C-reactive protein levels in Korean infants
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DOI: 10.1038/s41598-019-52070-3
Abstract: Urinary tract infection (UTI) is one of the most common bacterial infections in infants less than age 1 year. UTIs frequently recur and result in long-term effects include sepsis and renal scarring. Uropathogenic Escherichia coli… read more here.
Keywords: escherichia coli; reactive protein; induction; uropathogenic escherichia ... See more keywords
In silico analysis and in vivo assessment of a novel epitope-based vaccine candidate against uropathogenic Escherichia coli
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DOI: 10.1038/s41598-020-73179-w
Abstract: Uropathogenic Escherichia coli (UPEC) are common pathogens in urinary tract infections (UTIs), which show resistance to antibiotics. Therefore, there is a need for a vaccine to reduce susceptibility to the infection. In the present study,… read more here.
Keywords: escherichia coli; candidate; vaccine candidate; uropathogenic escherichia ... See more keywords
Human neutrophil peptides 1-3 protect the murine urinary tract from uropathogenic Escherichia coli challenge
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2206515119
Abstract: Significance Genetic variations can affect the immune response to infectious conditions. Recent evidence shows DNA copy number variations (CNVs) in the DEFA1A3 locus, which encodes for human neutrophil peptides 1-3 (HNP1-3) are associated with urinary… read more here.
Keywords: urinary tract; uropathogenic escherichia; tract; escherichia coli ... See more keywords
Comprehensive analysis of PNA-based antisense antibiotics targeting various essential genes in uropathogenic Escherichia coli
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DOI: 10.1093/nar/gkac362
Abstract: Antisense peptide nucleic acids (PNAs) that target mRNAs of essential bacterial genes exhibit specific bactericidal effects in several microbial species, but our mechanistic understanding of PNA activity and their target gene spectrum is limited. Here,… read more here.
Keywords: uropathogenic escherichia; pna; escherichia coli; analysis ... See more keywords
Uropathogenic Escherichia coli can cause cystitis at extremely low inocula in a pig model.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001537
Abstract: Urinary tract infection (UTI) is one of the most common bacterial infections worldwide. Experimental models that accurately reflect the high susceptibility to UTI in humans have, however, been lacking. This situation has limited detailed research… read more here.
Keywords: urinary tract; uropathogenic escherichia; escherichia coli; pig model ... See more keywords
Repurposing auranofin to combat uropathogenic Escherichia coli biofilms
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DOI: 10.1111/jam.14312
Abstract: The aim of this study was to assess anti‐biofilm and antimicrobial effects of auranofin, an anti‐rheumatic agent, on uropathogenic Escherichia coli (UPEC) biofilm formation. read more here.
Keywords: escherichia coli; uropathogenic escherichia; repurposing auranofin; auranofin combat ... See more keywords
Peptidoglycan Sensing Prevents Quiescence and Promotes Quorum-Independent Colony Growth of Uropathogenic Escherichia coli
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DOI: 10.1128/jb.00157-20
Abstract: Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections (UTIs). During pathogenesis, UPEC cells adhere to and infiltrate bladder epithelial cells, where they may form intracellular bacterial communities (IBCs) or enter a… read more here.
Keywords: uropathogenic escherichia; quiescent state; escherichia coli; state ... See more keywords