Combined treatment with pemetrexed and vinflunine in patients with metastatic urothelial cell carcinoma after prior platinum-containing chemotherapy – results of an exploratory phase I study
Sign Up to like & getrecommendations! Published in 2017 at "Investigational New Drugs"
DOI: 10.1007/s10637-017-0528-y
Abstract: SummaryVinflunine is to date the only registered agent for second-line treatment of metastatic urothelial cell carcinoma (UCC) in Europe. However, the effect is modest. Pemetrexed has demonstrated some single-agent activity in this disease entity. In… read more here.
Keywords: urothelial cell; cell carcinoma; treatment; vinflunine ... See more keywords
Enhanced clearing of Candida biofilms on a 3D urothelial cell in vitro model using lysozyme-functionalized fluconazole-loaded shellac nanoparticles.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials science"
DOI: 10.1039/d1bm01035b
Abstract: Candida urinary tract biofilms are increasingly witnessed in nosocomial infections due to reduced immunity of patients and the hospital ecosystem. The indwelling devices utilized to support patients with urethral diseases that connect the unsterilized external… read more here.
Keywords: urothelial cell; candida; model; biofilm ... See more keywords
Does reduced E-cadherin expression correlate with poor prognosis in patients with upper tract urothelial cell carcinoma?
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DOI: 10.1097/md.0000000000017377
Abstract: Abstract Background: E-cadherin has emerged as a prognostic factor of urothelial cell carcinoma. In the present work we investigate the relationship between expression of E-cadherin and clinical outcomes, following radical nephroureterectomy for upper tract urothelial… read more here.
Keywords: expression; reduced cadherin; urothelial cell; cell carcinoma ... See more keywords
Utility of lymph node dissection for clinical node negative upper tract urothelial cell carcinoma: A multicenter study.
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DOI: 10.1200/jco.2018.36.6_suppl.474
Abstract: 474Background: Upper tract urothelial cell carcinoma (UTUC) is an uncommon malignancy with disparate outcomes. Although use of lymph node dissection (LND) for urothelial cell carcinoma of the bladder has survival benefit even in setting of… read more here.
Keywords: urothelial cell; cell carcinoma; clinical node; node negative ... See more keywords
Sex-related differences in urothelial cell carcinoma of the bladder in Germany
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DOI: 10.2147/cmar.s181532
Abstract: Background Urothelial cell carcinoma (UCC), also called transitional cell cancer, occurs significantly more often in males than in females. Essential for the prognosis of recovery is depth of infiltration (muscle-invasive or non-muscle invasive) and tumor-differentiation… read more here.
Keywords: urothelial cell; carcinoma; sex related; bladder ... See more keywords
Protective Effect of Purinergic P2X7 Receptor Inhibition on Acrolein-Induced Urothelial Cell Damage
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DOI: 10.3389/fphys.2022.885545
Abstract: Patients undergoing chemotherapy with cyclophosphamide experience cystitis due to excretion of a toxic metabolite, acrolein. Cystitis, an inflammation of the bladder, is associated with damage to the integrity of the urothelial barrier. The purinergic P2X7… read more here.
Keywords: acrolein induced; cell; damage; urothelial cell ... See more keywords
Impact of tissue inhibitor of metalloproteinases-3 genetic variants on clinicopathological characteristics of urothelial cell carcinoma
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DOI: 10.7150/jca.81083
Abstract: To investigate the distribution of single nucleotide polymorphism (SNP) of tissue inhibitor of metalloproteinases-3 (TIMP-3) in patients with/without urothelial cell carcinoma (UCC), three loci of TIMP-3 SNPs (rs9862 C/T, rs9619311 T/C, rs11547635 C/T) were genotyped… read more here.
Keywords: cell carcinoma; urothelial cell; inhibitor metalloproteinases; tissue inhibitor ... See more keywords