Modulation of lower urinary tract smooth muscle contraction and relaxation by the urothelium
Sign Up to like & getrecommendations! Published in 2018 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-018-1510-8
Abstract: The epithelial inner layer of the lower urinary tract, i.e., the urothelium, and other parts of the mucosa are not just a passive barrier but play an active role in the sensing of stretching, neurotransmitters,… read more here.
Keywords: urothelium; lower urinary; smooth muscle; urinary tract ... See more keywords
PD-L2 Is Constitutively Expressed in Normal and Malignant Urothelium
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DOI: 10.3389/fonc.2021.626748
Abstract: The use of immune checkpoint blockade, in particular PD-1 and PD-L1 inhibitors, is now commonplace in many clinical settings including the treatment of muscle-invasive bladder cancer (MIBC). Notwithstanding, little information exists regarding the expression of… read more here.
Keywords: expressed normal; normal malignant; malignant urothelium; expression ... See more keywords
Aging-Associated Changes in Oxidative Stress Negatively Impacts the Urinary Bladder Urothelium
Sign Up to like & getrecommendations! Published in 2022 at "International Neurourology Journal"
DOI: 10.5213/inj.2142224.112
Abstract: Purpose Lower urinary tract symptoms are known to significantly increase with age, negatively impacting quality of life and self-reliance. The urothelium fulfills crucial tasks, serving as a barrier protecting the underlying bladder tissue from the… read more here.
Keywords: reactive oxygen; bladder; oxidative stress; aging associated ... See more keywords