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Published in 2022 at "Journal of Periodontology"
DOI: 10.1002/jper.22-0361
Abstract: Abstract A biologic is a therapeutic agent with biological activity that is administered to achieve an enhanced regenerative or reparative effect. The use of biologics has progressively become a core component of contemporary periodontal practice.…
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Keywords:
practice;
consensus;
use biologics;
periodontology ... See more keywords
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Published in 2017 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2017.04.011
Abstract: BACKGROUND/PURPOSE Despite conventional immunosuppressants, active and steroid-dependent systemic lupus erythematosus (SLE) represents a therapeutic challenge. Only one biologic, belimumab, has been approved, but other biologics are sometimes used off-label. Given the lack of evidence-based data…
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Keywords:
systemic lupus;
lupus erythematosus;
recommendations use;
expert recommendations ... See more keywords
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Published in 2021 at "European journal of internal medicine"
DOI: 10.1016/j.ejim.2021.10.028
Abstract: OBJECTIVE To describe the efficacy and safety of off-label use of biologics for refractory and/or relapsing granulomatosis with polyangiitis (GPA). METHODS We conducted a French retrospective study including GPA patients who received off-label biologics for…
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Keywords:
treatment;
refractory relapsing;
label use;
use biologics ... See more keywords
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Published in 2020 at "Operative Techniques in Sports Medicine"
DOI: 10.1016/j.otsm.2020.150761
Abstract: ABSTRACT The use of biologic adjuvants in orthopedic injuries continues to expand along with the comprehension of the healing and regeneration mechanisms of tissues. Biological treatments represent a potentially attractive option for a number of…
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Keywords:
outcomes hip;
improve outcomes;
biologics improve;
hip preservation ... See more keywords
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Published in 2018 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2018.1391787
Abstract: ABSTRACT Introduction: Childhood psoriasis is a special situation that is a management challenge for the treating dermatologist. As is the situation with traditional systemic agents, which are commonly used in managing severe psoriasis in children,…
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Keywords:
pediatric psoriasis;
safety;
biologics pediatric;
managing severe ... See more keywords
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Published in 2019 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000540
Abstract: PURPOSE OF REVIEW Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory condition with different endotypes between patients from eastern or western countries. Targeted biologics are currently used to treat CRSwNP, but the outcomes…
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Keywords:
nasal polyps;
biologics chronic;
use biologics;
chronic sinusitis ... See more keywords
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Published in 2022 at "Current Opinion in Pulmonary Medicine"
DOI: 10.1097/mcp.0000000000000861
Abstract: Purpose of review There are multiple FDA-approved biologics to treat poorly controlled moderate-to-severe asthma. Given the heterogeneity of asthma and the lack of head-to-head data between biologics, selecting the best biologic for a patient can…
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Keywords:
use biologics;
head;
moderate severe;
medicine use ... See more keywords
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Published in 2018 at "British Journal of Dermatology"
DOI: 10.1111/bjd.17022
Abstract: Compared with conventional systemic treatment modalities such as methotrexate, the superior efficacy and absence of cumulative toxicity have led to a widespread uptake and use of biologics for treatment of psoriasis and a number of…
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Keywords:
risk;
patients psoriasis;
treatment;
cancer ... See more keywords
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Published in 2020 at "Internal Medicine Journal"
DOI: 10.1111/imj.14799
Abstract: 1 Zagora S, McCluskey P. Biologic therapy for uveitis: a new beginning. Intern Med J 2019; 49: 1349–51. 2 Trivedi A, Katelaris C. The use of biologic agents in the management of uveitis. Intern Med…
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Keywords:
biologics non;
use;
infectious uveitis;
uveitis situation ... See more keywords
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Published in 2020 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2020.2238
Abstract: Introduction: Real-world data on the use and effectiveness of severe asthma biologics are useful as they confirm the findings of RCTs. The Cretan Registry of the use of Biologics in Severe Asthma (CREBS) is a…
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Keywords:
treatment;
severe asthma;
registry;
cretan registry ... See more keywords
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Published in 2022 at "ERJ Open Research"
DOI: 10.1183/23120541.00273-2022
Abstract: Introduction Treatment with biologics for severe asthma is informed by international and national guidelines and defined by national regulating bodies, but how these drugs are used in real-life is unknown. Materials and methods The European…
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Keywords:
use biologics;
europe;
heterogeneity use;
severe asthma ... See more keywords