Direct Use of Phosphonium Salts for Alkylation of p-Quinols: Formal α-Arylation of Carbonyls via a 5-Membered Betaine-Type Intermediate.
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DOI: 10.1021/acs.orglett.2c02638
Abstract: Unlike phosphonium ylides used extensively for C═C bond formation, herein we disclose the direct use of phosphonium salts for site-selective alkylation to p-quinols via a 5-membered betaine-type intermediate. This strategy provides a novel and general… read more here.
Keywords: phosphonium salts; phosphonium; alkylation quinols; use phosphonium ... See more keywords