Spiders Use Structural Conversion of Globular Amyloidogenic Domains to Make Strong Silk Fibers
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DOI: 10.1002/adfm.202315409
Abstract: Spider silk—an environmentally friendly protein‐based material—is widely recognized for its extraordinary mechanical properties. Biomimetic spider silk‐like fibers made from recombinant spider silk proteins (spidroins) currently falls short compared to natural silks in terms of mechanical… read more here.
Keywords: use structural; silk; spider silk; domains make ... See more keywords
Use of Structural Alerts for Reactive Metabolites in the Application SpotRM.
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DOI: 10.1021/acs.chemrestox.4c00205
Abstract: Reactive metabolite (RM) formation is widely accepted as playing a crucial role in causing idiosyncratic adverse drug reactions (IADRs), where the liver is most affected. An important goal of drug design is to avoid selection… read more here.
Keywords: structural alerts; use structural; alerts reactive; drug ... See more keywords