Use of Tofacitinib for infant-onset STING-associated vasculopathy: A case report from China
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DOI: 10.1097/md.0000000000031832
Abstract: Background: Stimulator of interferon gene (STING)-associated vasculopathy with onset in infancy (SAVI), caused by gain-of-function mutations in human transmembrane protein 173 (TMEM173), is characterized by widespread chronic inflammation primarily affecting the skin and lungs. Although… read more here.
Keywords: associated vasculopathy; sting associated; infant onset; tofacitinib infant ... See more keywords
Response to: ‘Off-label use of tofacitinib: a potential treatment option for SAPHO syndrome’ by Xie et al
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DOI: 10.1136/annrheumdis-2020-217956
Abstract: We would like to thank Xie et al 1 for their interest in our paper2 and for their insights into the possible mechanism of action of tofacitinib in synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO)… read more here.
Keywords: xie; sapho syndrome; use tofacitinib; label use ... See more keywords
AB0344 FACTORS WHICH CONTRIBUTE PERSISTENCY AND OPTIMAL USE OF TOFACITINIB; LESSONS FROM LONG TERM DAILY CLINICAL USE OF TOFACITINIB
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DOI: 10.1136/annrheumdis-2020-eular.2783
Abstract: Recently, tofacitinib treatment in rheumatoid arthritis (RA) is thought to be not inferior to other biologic disease-modifying antirheumatic drugs (bDMARDS) such as TNF-inhibitor. However, approval of tofacitinib for treatment with RA is relatively recent as… read more here.
Keywords: efficacy; use tofacitinib; disease; tofacitinib treatment ... See more keywords
First use of tofacitinib to treat an immune checkpoint inhibitor-induced arthritis
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DOI: 10.1136/bcr-2020-238851
Abstract: Immune checkpoint inhibitors have revolutionised cancer treatment; however, immune-related adverse events do occur, with up to 7% developing inflammatory arthritis. Common rheumatoid arthritis therapies such as methotrexate, prednisolone and biologics have been used to treat… read more here.
Keywords: immune checkpoint; inhibitor; use tofacitinib; first use ... See more keywords