Zebrafish as a tractable model of human cardiovascular disease.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of pharmacology"
DOI: 10.1111/bph.15473
Abstract: Mammalian models including non-human primates, pigs and rodents have been used extensively to study the mechanisms of cardiovascular disease. However, there is an increasing desire for alternative model systems that provide excellent scientific value while… read more here.
Keywords: zebrafish tractable; disease; physiology; model ... See more keywords
Use of Zebrafish Embryos To Reproduce Human Norovirus and To Evaluate Human Norovirus Infectivity Decay after UV Treatment
Sign Up to like & getrecommendations! Published in 2023 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.00115-23
Abstract: HNoVs are a leading cause of gastroenteritis outbreaks worldwide. The zebrafish embryo tool as developed in this study serves as an efficient way to generate viruses with high titers and clean background and a straightforward… read more here.
Keywords: hnov inactivation; hnov; evaluate; treatment ... See more keywords
Use of zebrafish models to investigate rare human disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Genetics"
DOI: 10.1136/jmedgenet-2018-105358
Abstract: Rare diseases are collectively common and often extremely debilitating. Following the emergence of next-generation sequencing (NGS) technologies, the variants underpinning rare genetic disorders are being unearthed at an accelerating rate. However, many rare conditions lack… read more here.
Keywords: large scale; rare diseases; disease; use zebrafish ... See more keywords
Fish tales: The use of zebrafish xenograft human cancer cell models.
Sign Up to like & getrecommendations! Published in 2017 at "Histology and histopathology"
DOI: 10.14670/hh-11-853
Abstract: Advances in scientific techniques have provided researchers with exceptional new opportunities to identify and monitor changes between different cancer types, during different stages of progression, between individual tumor cells and in the surrounding stroma. The… read more here.
Keywords: fish tales; use zebrafish; tales use; zebrafish xenograft ... See more keywords
Seeing the Light: The Use of Zebrafish for Optogenetic Studies of the Heart
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.748570
Abstract: Optogenetics, involving the optical measurement and manipulation of cellular activity with genetically encoded light-sensitive proteins (“reporters” and “actuators”), is a powerful experimental technique for probing (patho-)physiological function. Originally developed as a tool for neuroscience, it… read more here.
Keywords: use zebrafish; cardiac research; heart; optogenetic studies ... See more keywords