Adiponectin receptor agonist AdipoRon blocks skin inflamm-ageing by regulating mitochondrial dynamics.
Sign Up to like & getrecommendations! Published in 2021 at "Cell proliferation"
DOI: 10.1111/cpr.13155
Abstract: INTRODUCTION Skin is susceptible to senescence-associated secretory phenotype (SASP) and inflamm-ageing partly owing to the degeneration of mitochondria. AdipoRon (AR) has protective effects on mitochondria in metabolic diseases such as diabetes. We explored the role… read more here.
Keywords: used detect; aged skin; skin inflamm; inflamm ageing ... See more keywords
A hybrid method of tests coupled with simulations used to detect the working processes of an automotive engine from cycle to cycle in transient conditions
Sign Up to like & getrecommendations! Published in 2017 at "Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering"
DOI: 10.1177/0954407016685627
Abstract: To improve the actual performance of an automotive engine, an approach consisting of dynamic signal measurements coupled with gas dynamics–thermodynamics process simulations is proposed; this is used to detect the working processes of an automotive… read more here.
Keywords: used detect; engine; transient conditions; cycle ... See more keywords
TRIM3 inhibits P53 signaling in breast cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01630-z
Abstract: Background Beast cancer is the most common women cancer worldwide, while two third of them are ER alpha positive breast cancer. Among the ER alpha positive breast cancer, about 80% are P53 wild type, indicating… read more here.
Keywords: used detect; p53 signaling; breast cancer; cancer ... See more keywords
MINDY1 promotes bladder cancer progression by stabilizing YAP
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DOI: 10.1186/s12935-021-02095-4
Abstract: Background Bladder cancer is one of the most commonly diagnosed urological malignant tumor. The Hippo tumor suppressor pathway is highly conserved in mammals and plays an important role in carcinogenesis. YAP is one of major… read more here.
Keywords: bladder cancer; used detect; mindy1; yap ... See more keywords
TET2 Promotes Keloid Hyperplasia by Regulating 5hmC Modification in the TGFβ Promoter Region
Sign Up to like & getrecommendations! Published in 2023 at "Clinical, Cosmetic and Investigational Dermatology"
DOI: 10.2147/ccid.s409621
Abstract: Introduction As a kind of human unique benign skin tumour, keloid has caused great trouble to the physical and mental health of patients and is unfavourable for beautiful. The abnormal proliferation of fibroblasts is one… read more here.
Keywords: regulating 5hmc; proliferation; used detect; tet2 ... See more keywords
Free Fatty Acids Promote the Development of Prostate Cancer by Upregulating Peroxisome Proliferator-Activated Receptor Gamma
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Management and Research"
DOI: 10.2147/cmar.s236301
Abstract: Introduction As one of the most common forms of cancer that threatens men’s health, prostate cancer (PCa) is under a trend of increasing morbidity and mortality in most countries. More and more studies have pointed… read more here.
Keywords: pca; development; prostate cancer; used detect ... See more keywords
SIRT6-specific inhibitor OSS-128167 exacerbates diabetic cardiomyopathy by aggravating inflammation and oxidative stress
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2021.12006
Abstract: Diabetic cardiomyopathy (DCM) is a serious complication of diabetes, which importantly contributes to the increased mortality of patients with diabetes. The development of DCM is accompanied by numerous pathological mechanisms, including oxidative stress and chronic… read more here.
Keywords: used detect; oss 128167; diabetic cardiomyopathy; inhibitor oss ... See more keywords