Direct Catalytic Symmetrical, Unsymmetrical N,N-Dialkylation and Cyclization of Acylhydrazides Using Alcohols.
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DOI: 10.1021/acs.orglett.0c02369
Abstract: Herein, direct N,N-dialkylation of acylhydrazides using alcohols is reported. This catalytic protocol provides one-pot synthesis of both symmetrical and unsymmetrical N,N-disubstituted acylhydrazides using an assortment of primary and secondary alcohols with remarkable selectivity and excellent… read more here.
Keywords: acylhydrazides using; dialkylation; cyclization acylhydrazides; using alcohols ... See more keywords
Iridium-Catalyzed C-Alkylation of Methyl Group on N-Heteroaromatic Compounds using Alcohols.
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DOI: 10.1021/acs.orglett.0c02635
Abstract: In this study, we developed a catalytic system for the C-alkylation of a methyl group on N-heteroaromatic compounds, including pyridine, pyrimidine, pyrazine, quinoline, quinoxaline, and isoquinoline, using alcohols based on a hydrogen-borrowing process with [Cp*IrCl2]2… read more here.
Keywords: group heteroaromatic; methyl group; heteroaromatic compounds; alkylation methyl ... See more keywords
Using alcohols as simple H2-equivalents for copper-catalysed transfer semihydrogenations of alkynes.
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DOI: 10.1039/c9cc06637c
Abstract: Copper(i)/N-heterocyclic carbene complexes enable a transfer semihydrogenation of alkynes employing simple and readily available alcohols such as isopropanol. The practical overall protocol circumvents the use of commonly employed high pressure equipment when using dihydrogen (H2)… read more here.
Keywords: alcohols simple; equivalents copper; copper; transfer ... See more keywords