GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1013
Abstract: Abstract G protein-coupled receptors (GPCRs) are physiologically abundant signaling hubs routing hundreds of extracellular signal substances and drugs into intracellular pathways. The GPCR database, GPCRdb supports >5000 interdisciplinary researchers every month with reference data, analysis,… read more here.
Keywords: gpcrdb; structure models; structure; state specific ... See more keywords
Protein Loop Modeling Using AlphaFold2.
Sign Up to like & getrecommendations! Published in 2023 at "IEEE/ACM transactions on computational biology and bioinformatics"
DOI: 10.1109/tcbb.2023.3264899
Abstract: The functions of proteins are largely determined by their three-dimensional (3D) structures. Loop modeling tries to predict the conformation of a relatively short stretch of protein backbone and sidechain. It is a difficult problem due… read more here.
Keywords: loop modeling; loop; protein loop; using alphafold2 ... See more keywords