Aromatic Halogenation by Using Bifunctional Flavin Reductase–Halogenase Fusion Enzymes
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201700391
Abstract: The remarkable site selectivity and broad substrate scope of flavin‐dependent halogenases (FDHs) has led to much interest in their potential as biocatalysts. Multiple engineering efforts have demonstrated that FDHs can be tuned for non‐native substrate… read more here.
Keywords: flavin reductase; using bifunctional; reductase; halogenation using ... See more keywords
Sequential ortho-C-H and ipso-C-O Functionalization Using a Bifunctional Directing Group.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b02910
Abstract: Design of C-H activation directing groups that can serve as electrophiles for subsequent cross-coupling significantly improves the step economy of synthetic applications of directed C-H functionalization. Through using a well-defined bifunctional template, palladium-catalyzed ortho-C-H alkenylation… read more here.
Keywords: functionalization using; using bifunctional; sequential ortho; ipso functionalization ... See more keywords