Visualizing Single-Nucleotide Variations in a Nuclear Genome Using Colocalization of Dual-Engineered CRISPR Probes.
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DOI: 10.1021/acs.analchem.2c01208
Abstract: Direct visualization of single-nucleotide variation (SNV) in single cells is of great importance for understanding the spatial organization of genomes and their relationship with cell phenotypes. Herein, we developed a new strategy for visualizing SNVs… read more here.
Keywords: nuclear genome; colocalization; using colocalization; single nucleotide ... See more keywords