Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data.
Sign Up to like & getrecommendations! Published in 2018 at "Nature protocols"
DOI: 10.1038/nprot.2017.146
Abstract: This protocol describes a workflow for creating structural models of proteins or protein complexes using distance restraints derived from cross-linking mass spectrometry experiments. The distance restraints are used (i) to adjust preliminary models that are… read more here.
Keywords: restraints derived; cross; using distance; cross linking ... See more keywords
Enhancing Protein Conformational Space Sampling Using Distance Profile-Guided Differential Evolution
Sign Up to like & getrecommendations! Published in 2017 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2016.2566617
Abstract: De novo protein structure prediction aims to search for low-energy conformations as it follows the thermodynamics hypothesis that places native conformations at the global minimum of the protein energy surface. However, the native conformation is… read more here.
Keywords: distance profile; energy; distance; conformation ... See more keywords