Copper-Mediated ortho-C-H Amination Using DMF as the Amine Source.
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DOI: 10.1021/acs.orglett.1c03223
Abstract: We report herein a copper-mediated ortho-C-H amination of anilines using oxalamide as the directing group and DMF as the amination reagent. This protocol tolerates various functional groups and shows good heterocyclic compatibility. Late-stage dimethylamination of… read more here.
Keywords: using dmf; copper mediated; ortho amination; amination ... See more keywords