Modeling Podocyte Biology Using Drosophila Nephrocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9841-8_2
Abstract: Vertebrate podocytes are kidney glomerular cells critically required for normal renal filtration. To fulfill their role, podocytes form molecular sieves known as slit diaphragms that contribute to the glomerular filtration barrier. The disruption of podocyte… read more here.
Keywords: using drosophila; modeling podocyte; biology; podocyte biology ... See more keywords
Using Drosophila Models and Tools to Understand the Mechanisms of Novel Human Cancer Driver Gene Function.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-23629-8_2
Abstract: The formation, overgrowth and metastasis of tumors comprise a complex series of cellular and molecular events resulting from the combined effects of a variety of aberrant signaling pathways, mutations, and epigenetic alterations. Modeling this complexity… read more here.
Keywords: drosophila models; models tools; using drosophila; cancer driver ... See more keywords
Functional analysis of glycosylation using Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2019 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-019-09892-0
Abstract: The glycosylation of proteins and lipids has various essential roles in a diverse range of biological processes, including embryogenesis, organ development, neurogenesis, maintenance of homeostasis, immune response, and tumorigenesis. Drosophila melanogaster is one of the… read more here.
Keywords: using drosophila; drosophila melanogaster; functional analysis; analysis glycosylation ... See more keywords
Studies of neurodegenerative diseases using Drosophila and the development of novel approaches for their analysis
Sign Up to like & getrecommendations! Published in 2022 at "Fly"
DOI: 10.1080/19336934.2022.2087484
Abstract: ABSTRACT The use of Drosophila in neurodegenerative disease research has contributed to the identification of modifier genes for the pathology. The basis for neurodegenerative disease occurrence in Drosophila is the conservation of genes across species… read more here.
Keywords: studies neurodegenerative; development; drosophila; analysis ... See more keywords
Toxicity Assessment of Curculigo orchioides Leaf Extract Using Drosophila melanogaster: A Preliminary Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph192215218
Abstract: Curculigo orchioides is used in Indian and Chinese traditional medicinal systems for various health benefits. However, its toxicological effects are mostly unknown. This study assesses the potential toxicity of aqueous leaf (A.L.) extract of C.… read more here.
Keywords: leaf extract; extract; toxicity; using drosophila ... See more keywords