Predicting genes from phenotypes using human phenotype ontology (HPO) terms.
Sign Up to like & getrecommendations! Published in 2022 at "Human genetics"
DOI: 10.1007/s00439-022-02449-6
Abstract: The interpretation of genomic variants following whole exome sequencing (WES) can be aided using human phenotype ontology (HPO) terms to standardize clinical features and predict causative genes. We performed WES on 453 patients diagnosed prior… read more here.
Keywords: using human; class; gene; hpo terms ... See more keywords
Studying human disease using human neurons
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research"
DOI: 10.1016/j.brainres.2016.03.051
Abstract: Utilizing patient derived cells has enormous promise for discovering new drugs for diseases of the nervous system, a goal that has been historically quite challenging. In this review, we will outline the potential of human… read more here.
Keywords: human neurons; using human; disease; disease using ... See more keywords
Anterior Glenohumeral Capsular Reconstruction Using a Human Acellular Dermal Allograft
Sign Up to like & getrecommendations! Published in 2018 at "Arthroscopy Techniques"
DOI: 10.1016/j.eats.2018.08.002
Abstract: Anterior capsular reconstruction needs to be done for most cases of anterior shoulder instability. Several surgical techniques using tendinous allografts and autografts have been used for the treatment of anterior glenohumeral capsular reconstruction. However, the… read more here.
Keywords: reconstruction; using human; capsular reconstruction; human acellular ... See more keywords
Constructing and Deconstructing Cancers using Human Pluripotent Stem Cells and Organoids.
Sign Up to like & getrecommendations! Published in 2019 at "Cell stem cell"
DOI: 10.1016/j.stem.2018.11.012
Abstract: Cell lines and animal models have provided the foundation of cancer research for many years. However, human pluripotent stem cells (hPSCs) and organoids are increasingly enabling insights into tumor development, progression, and treatment. Here, we… read more here.
Keywords: human pluripotent; constructing deconstructing; using human; pluripotent stem ... See more keywords
GWAS signals revisited using human knockouts
Sign Up to like & getrecommendations! Published in 2018 at "Genetics in Medicine"
DOI: 10.1038/gim.2017.78
Abstract: PurposeGenome-wide association studies (GWAS) have been instrumental to our understanding of the genetic risk determinants of complex traits. A common challenge in GWAS is the interpretation of signals, which are usually attributed to the genes… read more here.
Keywords: gwas signals; interpretation; signals revisited; using human ... See more keywords
Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-11506-4
Abstract: Fibromyalgia is a refractory disease characterized by chronic intractable pain and psychological suffering, the cause of which has not yet been elucidated due to its complex pathology. Activation of immune cells in the brain called… read more here.
Keywords: using human; research using; img cells; pathology ... See more keywords
The consistency of aminotransferase analysis in China: a comparison of six mainstream aminotransferase routine methods and recalibration using human pooled serum preparations supplemented with human recombinant aminotransferases
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2025895
Abstract: Abstract Background: To evaluate the consistency of six mainstream homogeneous systems for aminotransferase measurements and improve the consistency of measurements by applying uniform calibrators. Methods: 200 individual samples were grouped into four sets for assays… read more here.
Keywords: using human; aminotransferase; group; recalibration ... See more keywords
FRESH 3D bioprinting a contractile heart tube using human stem cell-derived cardiomyocytes
Sign Up to like & getrecommendations! Published in 2022 at "Biofabrication"
DOI: 10.1088/1758-5090/ac58be
Abstract: Here we report the 3D bioprinting of a simplified model of the heart, similar to that observed in embryonic development, where the heart is a linear tube that pumps blood and nutrients to the growing… read more here.
Keywords: using human; heart tube; heart; tube using ... See more keywords
Insights into amebiasis using a human 3D‐intestinal model
Sign Up to like & getrecommendations! Published in 2020 at "Cellular Microbiology"
DOI: 10.1111/cmi.13203
Abstract: Entamoeba histolytica is the causative agent of amebiasis, an infectious disease targeting the intestine and the liver in humans. Two types of intestinal infection are caused by this parasite: silent infection, which occurs in the… read more here.
Keywords: intestinal model; using human; model; amebiasis using ... See more keywords
Training in cardiac surgery using human cadavers: Effectiveness of “Silent Teachers”
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiac Surgery"
DOI: 10.1111/jocs.14005
Abstract: Surgical skills acquisition in cardiac surgery requires consistent and hard practice. Furthermore, training using cadaver is advocated as a means of transferring learned skills to the operating room and recreate surgical situations for trainees to… read more here.
Keywords: surgery; surgery using; human cadavers; using human ... See more keywords
Using Human–Machine Interfaces to Convey Feedback in Automated Driving
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cognitive Engineering and Decision Making"
DOI: 10.1177/15553434221076827
Abstract: The next decade will see a rapid increase in the prevalence of partial vehicle automation, specifically conditional automation (i.e., SAE level 3; SAE, 2018). In conditional automation, the expectation is that the user is still… read more here.
Keywords: human machine; automation; using human; control ... See more keywords