Conversion of glycals into vicinal-1,2-diazides and 1,2-(or 2,1)-azidoacetates using hypervalent iodine reagents and Me3SiN3. Application in the synthesis of N-glycopeptides, pseudo-trisaccharides and an iminosugar
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DOI: 10.1039/c7ra08637g
Abstract: Glycals were found to react with a reagent system comprising of phenyliodine bis(trifluoroacetate) (PIFA) and Me3SiN3 in the presence of TMSOTf as a catalyst to form the corresponding vicinal 1,2-diazides. On the other hand, they… read more here.
Keywords: vicinal diazides; using hypervalent; diazides azidoacetates; azidoacetates using ... See more keywords
Enantioselective iodolactonization to prepare ε-lactone rings using hypervalent iodine
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DOI: 10.1039/d2sc01587k
Abstract: Despite the rapid growth of enantioselective halolactonization reactions in recent years, most are effective only when forming smaller (6,5,4-membered) rings. Seven-membered ε-lactones, are rarely formed with high selectivity, and never without conformational bias. We describe… read more here.
Keywords: prepare lactone; rings using; enantioselective iodolactonization; using hypervalent ... See more keywords
Synthesis of Sulfoximines and Sulfonimidamides Using Hypervalent Iodine Mediated NH Transfer
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DOI: 10.3390/molecules28031120
Abstract: The development of NH transfer reactions using hypervalent iodine and simple sources of ammonia has facilitated the synthesis of sulfoximines and sulfonimidamides for applications across the chemical sciences. Perhaps most notably, the methods have been… read more here.
Keywords: transfer; hypervalent iodine; using hypervalent; synthesis sulfoximines ... See more keywords