Predicting drug-target interactions using Lasso with random forest based on evolutionary information and chemical structure.
Sign Up to like & getrecommendations! Published in 2018 at "Genomics"
DOI: 10.1016/j.ygeno.2018.12.007
Abstract: The identification of drug-target interactions has great significance for pharmaceutical scientific research. Since traditional experimental methods identifying drug-target interactions is costly and time-consuming, the use of machine learning methods to predict potential drug-target interactions has… read more here.
Keywords: target; drug; drug target; target interactions ... See more keywords
Using Lasso and Adaptive Lasso to Identify DIF in Multidimensional 2PL Models.
Sign Up to like & getrecommendations! Published in 2022 at "Multivariate behavioral research"
DOI: 10.1080/00273171.2021.1985950
Abstract: Differential item functioning (DIF) analysis refers to procedures that evaluate whether an item's characteristic differs for different groups of persons after controlling for overall differences in performance. DIF is routinely evaluated as a screening step… read more here.
Keywords: lasso; adaptive lasso; lasso adaptive; regularization methods ... See more keywords