Measurement of brain lactate during visual stimulation using a long TE semi‐LASER sequence at 7 T
Sign Up to like & getrecommendations! Published in 2020 at "Nmr in Biomedicine"
DOI: 10.1002/nbm.4223
Abstract: Estimation of metabolic changes during neuronal activation represents a challenge for in vivo MRS, especially for metabolites with low concentration and signal overlap, such as lactate. In this work, we aimed to evaluate the feasibility… read more here.
Keywords: laser sequence; using long; visual stimulation; semi laser ... See more keywords
Virtual sensing method for monitoring vibration of continuously variable configuration structures using long short-term memory networks
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Aeronautics"
DOI: 10.1016/j.cja.2019.09.013
Abstract: Abstract Vibration monitoring by virtual sensing methods has been well developed for linear time-invariant structures with limited sensors. However, few methods are proposed for Time-Varying (TV) structures which are inevitable in aerospace engineering. The core… read more here.
Keywords: using long; configuration; vibration; virtual sensing ... See more keywords
De novo diploid genome assembly using long noisy reads
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-47349-7
Abstract: The high sequencing error rate has impeded the application of long noisy reads for diploid genome assembly. Most existing assemblers failed to generate high-quality phased assemblies using long noisy reads. Here, we present PECAT, a… read more here.
Keywords: diploid genome; genome assembly; noisy reads; using long ... See more keywords
Reconstructing viral haplotypes using long reads
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac089
Abstract: MOTIVATION Most RNA viruses lack strict proofreading during replication. Coupled with a high replication rate, some RNA viruses can form a virus population containing a group of genetically-related but different haplotypes. Characterizing the haplotype composition… read more here.
Keywords: using long; haplotypes using; viral haplotypes; reconstructing viral ... See more keywords
Identification of phytoplankton isolates from the eastern Canadian waters using long-read sequencing
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Plankton Research"
DOI: 10.1093/plankt/fbae043
Abstract: Abstract As important primary producers and key components of biogeochemical processes, phytoplankton communities are highly diverse and continually adapt to changes in the environment, impacting the entire marine ecosystem. Consequently, it remains important to isolate,… read more here.
Keywords: phytoplankton; long read; canadian waters; eastern canadian ... See more keywords
Homology-Directed Repair by CRISPR-Cas9 Mutagenesis in Xenopus Using Long Single-Stranded Donor DNA Templates via Simple Microinjection of Embryos.
Sign Up to like & getrecommendations! Published in 2022 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.prot107599
Abstract: We describe a step-by-step procedure to perform homology-directed repair (HDR)-mediated precise gene editing in Xenopus embryos using long single-stranded DNA (lssDNA) as a donor template for HDR in conjunction with the CRISPR-Cas9 system. A key… read more here.
Keywords: using long; long single; single stranded; xenopus ... See more keywords
LRScaf: improving draft genomes using long noisy reads
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-6337-2
Abstract: BackgroundThe advent of third-generation sequencing (TGS) technologies opens the door to improve genome assembly. Long reads are promising for enhancing the quality of fragmented draft assemblies constructed from next-generation sequencing (NGS) technologies. To date, a… read more here.
Keywords: draft; using long; contiguity; improving draft ... See more keywords
TRsv: simultaneous detection of tandem repeat variations, structural variations, and short indels using long read sequencing data
Sign Up to like & getrecommendations! Published in 2025 at "Genome Biology"
DOI: 10.1186/s13059-025-03718-z
Abstract: Tandem repeat copy number variations (TR-CNVs), structural variations (SVs), and short indels have been responsible for many diseases and traits, but no tools exist to distinguish and detect these variants. In this study, we developed… read more here.
Keywords: detection; using long; structural variations; indels using ... See more keywords
Lower Limb Kinematics Trajectory Prediction Using Long Short-Term Memory Neural Networks
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00362
Abstract: This study determined whether the kinematics of lower limb trajectories during walking could be extrapolated using long short-term memory (LSTM) neural networks. It was hypothesised that LSTM auto encoders could reliably forecast multiple time-step trajectories… read more here.
Keywords: using long; lower limb; long short; kinematics ... See more keywords
Using Long-Term Follow-Up Data to Classify Genetic Variants in Newborn Screened Conditions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.859837
Abstract: With the rapid increase in publicly available sequencing data, healthcare professionals are tasked with understanding how genetic variation informs diagnosis and affects patient health outcomes. Understanding the impact of a genetic variant in disease could… read more here.
Keywords: long term; using long; genetic variants; follow data ... See more keywords
Unique Molecular Identifier-Based High-Resolution HLA Typing and Transcript Quantitation Using Long-Read Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.901377
Abstract: HLA typing provides essential results for stem cell and solid organ transplants, as well as providing diagnostic benefits for various rheumatology, gastroenterology, neurology, and infectious diseases. It is becoming increasingly clear that understanding the expression… read more here.
Keywords: using long; hla typing; hla; expression ... See more keywords