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Published in 2024 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70630
Abstract: Deep sequencing of the whole hepatitis B virus genome increases the analytical resolution and has the potential to improve molecular epidemiology investigations. The aim of this study was to develop and evaluate the performance of… read more here.
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Published in 2023 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2023.2173243
Abstract: PURPOSE We establish an accurate and rapid diagnostic method for pathogen detection in infectious uveitis using nanopore metagenomic next-generation sequencing (NGS). METHODS In eight patients with suspected infectious uveitis, we prospectively compared the accuracy and… read more here.
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Published in 2025 at "AIDS Research and Human Retroviruses"
DOI: 10.1089/aid.2024.0108
Abstract: Recombination contributes substantially to the genetic diversity of HIV-1. Here we reported a novel HIV-1 recombinant detected from a Chinese labor who had been to Uganda as an immigrant worker using nanopore sequencing. Near full-length… read more here.
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Published in 2021 at "Methods in Ecology and Evolution"
DOI: 10.1111/2041-210x.13561
Abstract: Metabarcoding has become a common approach to the rapid identification of the species composition in a mixed sample. The majority of studies use established short‐read high‐throughput sequencing platforms. The Oxford Nanopore MinIONTM, a portable sequencing… read more here.
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Published in 2020 at "Journal of integrative plant biology"
DOI: 10.1111/jipb.13002
Abstract: N6 -methyladenosine (m6 A) is a prevalent modification in messenger RNAs and circular RNAs that plays important roles in regulating various aspects of RNA metabolism. However, the occurrence of the m6 A modification in plant… read more here.
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Published in 2024 at "Journal of Medical Genetics"
DOI: 10.1136/jmg-2023-109832
Abstract: Background Facioscapulohumeral muscular dystrophy 1 (FSHD1) is an autosomal dominant muscular disorder mainly caused by the contraction and hypomethylation of the D4Z4 repeat array in chromosome 4q35. Prenatal diagnosis of FSHD1 is challenging due to… read more here.
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Published in 2022 at "Journal of Perinatal Medicine"
DOI: 10.1515/jpm-2022-0504
Abstract: Abstract Objectives Early diagnosis and treatment of intra-amniotic infection is crucial. Rapid pathogen identification allows for a definite diagnosis and enables proper management. We determined whether the 16S amplicon sequencing performed by a nanopore sequencing… read more here.
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Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.867018
Abstract: Occurrence of extra-chromosomal circular DNA is a phenomenon frequently observed in tumor cells, and the presence of such DNA has been recognized as a marker of adverse outcome across cancer types. We here describe a… read more here.
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.814806
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread and poses a major threat to public health worldwide. The whole genome sequencing plays a crucial role in virus surveillance and evolutionary analysis. In this… read more here.
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Published in 2024 at "International journal of mycobacteriology"
DOI: 10.4103/ijmy.ijmy_139_24
Abstract: BACKGROUND Phenotypic drug susceptibility testing (DST) is considered the gold standard for detecting linezolid (LZD) resistance in Mycobacterium tuberculosis (MTB), but it is time-consuming. Nanopore sequencing offers a potentially faster alternative approach. This study evaluated… read more here.