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   Articles with "using nmr" as a keyword



Exploring metabolic responses and pathway changes in CHO‐K1 cells under varied aeration conditions and copper supplementations using 1H NMR‐based metabolomics

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recommendations! Published in 2024 at "Biotechnology Journal"

DOI: 10.1002/biot.202300495

Abstract: The optimization of bioprocess for CHO cell culture involves careful consideration of factors such as nutrient consumption, metabolic byproduct accumulation, cell growth, and monoclonal antibody (mAb) production. Valuable insights can be obtained by understanding cellular… read more here.

Keywords: based metabolomics; using nmr; culture; cell ... See more keywords
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Plant Metabolomics Using NMR Spectroscopy.

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recommendations! Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9690-2_19

Abstract: The major goal in plant metabolomics is to study complex extracts for the purposes of metabolic exploration and natural products discovery. To achieve this goal, plant metabolomics relies on accurate and selective acquisition of all possible… read more here.

Keywords: plant; plant metabolomics; using nmr; metabolomics using ... See more keywords

128. Detection of predictive makers for preeclampsia using NMR and GC–MS/MS metabolomics

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recommendations! Published in 2018 at "Pregnancy Hypertension"

DOI: 10.1016/j.preghy.2018.08.075

Abstract: Introduction The Birth and Three Generation Cohort Study was initiated by Tohoku Medical Megabank Organization (ToMMo), Tohoku University, Japan. A total of 73 085 participants, spanning 3 generations and including 22 493 pregnant women, have… read more here.

Keywords: onset; developed preeclampsia; using nmr; pregnant women ... See more keywords

Whole Body Distribution of Labile Coenzymes and Antioxidants in a Mouse Model as Visualized Using 1H NMR Spectroscopy.

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recommendations! Published in 2023 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.3c00054

Abstract: Coenzyme A, acetyl coenzyme A, coenzymes of cellular energy, coenzymes of redox reactions, and antioxidants mediate biochemical reactions fundamental to the functioning of all living cells. There is an immense interest in measuring them routinely… read more here.

Keywords: spectroscopy; using nmr; distribution labile; mouse model ... See more keywords

Protein Allostery Study in Cells Using NMR Spectroscopy.

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recommendations! Published in 2024 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.4c00360

Abstract: Protein allostery is commonly observed in vitro. But how protein allostery behaves in cells is unknown. In this work, a protein monomer-dimer equilibrium system was built with the allosteric effect on the binding characterized using… read more here.

Keywords: spectroscopy; nmr spectroscopy; using nmr; protein allostery ... See more keywords

Visualization of Early and Late Molecular Events Associated with the Development of Type 1 Diabetes Using NMR Spectroscopy.

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recommendations! Published in 2025 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.5c00301

Abstract: Type 1 diabetes mellitus (T1DM) is an autoimmune disorder caused by the loss of insulin-producing pancreatic β-cells. This study aims to explore the correlation between hyperglycemia and concurrent metabolic perturbations during T1DM development to help… read more here.

Keywords: spectroscopy; using nmr; type diabetes; nmr spectroscopy ... See more keywords

Using NMR to Monitor TET-Dependent Methylcytosine Dioxygenase Activity and Regulation.

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recommendations! Published in 2024 at "ACS chemical biology"

DOI: 10.1021/acschembio.3c00619

Abstract: The active removal of DNA methylation marks is governed by the ten-eleven translocation (TET) family of enzymes (TET1-3), which iteratively oxidize 5-methycytosine (5mC) into 5-hydroxymethycytosine (5hmC), and then 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). TET proteins… read more here.

Keywords: nmr monitor; using nmr; activity; regulation ... See more keywords

Evaluating antimalarial efficacy by tracking glycolysis in Plasmodium falciparum using NMR spectroscopy

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-36197-3

Abstract: Glucose is an essential nutrient for Plasmodium falciparum and robust glycolytic activity is indicative of viable parasites. Using NMR spectroscopy, we show that P. falciparum infected erythrocytes consume ~20 times more glucose, and trophozoites metabolize… read more here.

Keywords: using nmr; falciparum; nmr spectroscopy; plasmodium falciparum ... See more keywords

Assessment of metabolic phenotypic variability in children’s urine using 1H NMR spectroscopy

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep46082

Abstract: The application of metabolic phenotyping in clinical and epidemiological studies is limited by a poor understanding of inter-individual, intra-individual and temporal variability in metabolic phenotypes. Using 1H NMR spectroscopy we characterised short-term variability in urinary… read more here.

Keywords: assessment metabolic; using nmr; nmr spectroscopy; variability ... See more keywords

Screening of Altered Metabolites and Metabolic Pathways in Celiac Disease Using NMR Spectroscopy

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recommendations! Published in 2021 at "BioMed Research International"

DOI: 10.1155/2021/1798783

Abstract: Background Celiac disease (CeD) is an autoimmune intestinal disorder caused by gluten protein consumption in genetically predisposed individuals. As biopsy sampling is an invasive procedure, finding novel noninvasive serological markers for screening of at-risk CeD… read more here.

Keywords: metabolism; healthy controls; using nmr; celiac disease ... See more keywords

The Investigation of Metabonomic Pathways of Serum of Iranian Women with Recurrent Miscarriage Using 1H NMR

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recommendations! Published in 2021 at "BioMed Research International"

DOI: 10.1155/2021/3422138

Abstract: Purpose Recurrent miscarriage applies to pregnancy loss expulsion of the fetus within the first 24 weeks of pregnancy. This study is aimed at comparatively investigating the sera of women with RM with those who have… read more here.

Keywords: metabonomic pathways; recurrent miscarriage; using nmr; spectroscopy ... See more keywords