Articles with "using parp" as a keyword



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Abstract IA23: Using PARP inhibitors to target ATM-deficient cancers

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Published in 2017 at "Molecular Cancer Research"

DOI: 10.1158/1557-3125.dnarepair16-ia23

Abstract: The Ataxia-Telangiectasia Mutated (ATM) serine/threonine protein kinase plays an important role in orchestrating the cellular response to DNA double strand breaks (DSBs). Germline loss of ATM function results in Ataxia-Telangiectasia (A-T), a devastating childhood syndrome… read more here.

Keywords: parp inhibitors; using parp; cancer; atm deficient ... See more keywords