Abstract IA23: Using PARP inhibitors to target ATM-deficient cancers
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DOI: 10.1158/1557-3125.dnarepair16-ia23
Abstract: The Ataxia-Telangiectasia Mutated (ATM) serine/threonine protein kinase plays an important role in orchestrating the cellular response to DNA double strand breaks (DSBs). Germline loss of ATM function results in Ataxia-Telangiectasia (A-T), a devastating childhood syndrome… read more here.
Keywords: parp inhibitors; using parp; cancer; atm deficient ... See more keywords