Typing tumors using pathways selected by somatic evolution
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DOI: 10.1038/s41467-018-06464-y
Abstract: Many recent efforts to analyze cancer genomes involve aggregation of mutations within reference maps of molecular pathways and protein networks. Here, we find these pathway studies are impeded by molecular interactions that are functionally irrelevant… read more here.
Keywords: using pathways; evolution; tumors using; cancer ... See more keywords