Prediction of N-linked glycosylation sites using position relative features and statistical moments
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DOI: 10.1371/journal.pone.0181966
Abstract: Glycosylation is one of the most complex post translation modification in eukaryotic cells. Almost 50% of the human proteome is glycosylated as glycosylation plays a vital role in various biological functions such as antigen’s recognition,… read more here.
Keywords: sites using; linked glycosylation; glycosylation; using position ... See more keywords
Glycoconjugation of Quinoline Derivatives Using the C-6 Position in Sugars as a Strategy for Improving the Selectivity and Cytotoxicity of Functionalized Compounds
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DOI: 10.3390/molecules27206918
Abstract: Based on the Warburg effect and the increased demand for glucose by tumor cells, a targeted drug delivery strategy was developed. A series of new glycoconjugates with increased ability to interact with GLUT transporters, responsible… read more here.
Keywords: cytotoxicity; cancer cells; using position; strategy ... See more keywords