A discovery-based metabolomic approach using UHPLC Q-TOF MS/MS unveils a plethora of prospective antihypertensive compounds in Korean fermented soybeans
Sign Up to like & getrecommendations! Published in 2021 at "Lwt - Food Science and Technology"
DOI: 10.1016/j.lwt.2020.110399
Abstract: Abstract Treating soybean with proteases and subsequent fermentation increases the release of bioactive compounds that may be strongly attached to the food matrix. In our quest to choose the best material to develop an antihypertensive… read more here.
Keywords: uhplc tof; discovery based; metabolomic approach; approach using ... See more keywords
Study on Urine Metabolic Profile of Aβ25–35-Induced Alzheimer's Disease Using UHPLC-Q-TOF-MS
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.10.001
Abstract: Alzheimer's disease (AD) is a progressive neurodegenerative disorder, with no effective method for its treatment so far. The pathogenesis of AD has been reported, but the endogenous metabolic profile and disease-related biomarkers are still not… read more here.
Keywords: uhplc tof; alzheimer disease; disease; metabolic profile ... See more keywords
Application of nDATA Workflow for Semi-Quantitative Screening of 1094 Pesticide Residues in Fruits and Vegetables Using UHPLC/ESI Q-Orbitrap Full MS/vDIA.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsaf009
Abstract: BACKGROUND Cost-effective multi-residue pesticide methods with a broad detection scope are desired for risk-based monitoring programs. OBJECTIVE The aim was to evaluate the nDATA (non-target Data Acquisition for Target Analysis) workflow using UHPLC/ESI quadrupole-Orbitrap (Q-Orbitrap)… read more here.
Keywords: esi orbitrap; orbitrap; vdia; uhplc esi ... See more keywords
Identification of Serum Metabolomics Characteristics in Patients with Stable Angina Pectoris Using UHPLC-QE-MS
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/3900828
Abstract: Background Stable angina pectoris (SAP) is one of the main types of coronary heart disease (CHD). To improve treatment outcomes, more effective biomarkers are needed. Currently, studies on the metabolic characteristics of SAP are lacking.… read more here.
Keywords: using uhplc; angina pectoris; stable angina; patients sap ... See more keywords
Exploration of Lipid Metabolism Alterations in Children with Active Tuberculosis Using UHPLC-MS/MS
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Immunology Research"
DOI: 10.1155/2023/8111355
Abstract: Metabolic profiling using nonsputum samples has demonstrated excellent performance in diagnosing infectious diseases. But little is known about the lipid metabolism alternation in children with tuberculosis (TB). Therefore, the study was performed to explore lipid… read more here.
Keywords: using uhplc; tuberculosis; lipid metabolism; metabolism alterations ... See more keywords
Simultaneous Quantification of Antipsychotic and Antiepileptic Drugs and Their Metabolites in Human Saliva Using UHPLC-DAD
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24162953
Abstract: Neuroleptics and antiepileptics are excreted in saliva, which can, therefore, be very useful in determining their concentration in the body. This study presents a method developed to simultaneously identify five neuroleptics—olanzapine, quetiapine, risperidone, aripiprazole, and… read more here.
Keywords: saliva; simultaneous quantification; antipsychotic antiepileptic; quantification antipsychotic ... See more keywords
Integration Viewpoint Using UHPLC-MS/MS, In Silico Analysis, Network Pharmacology, and In Vitro Analysis to Evaluate the Bio-Potential of Muscari armeniacum Extracts
Sign Up to like & getrecommendations! Published in 2025 at "Molecules"
DOI: 10.3390/molecules30132855
Abstract: The current study investigates the chemical profiling, antioxidant activities, and enzyme inhibitory and cytotoxic potential of the water and methanolic extracts of different parts (flower, leaf, and bulb) of Muscari armeniacum. Chemical profiling was performed… read more here.
Keywords: analysis; pharmacology; muscari armeniacum; bulb ... See more keywords
Using UHPLC–MS profiling for the discovery of new sponge-derived metabolites and anthelmintic screening of the NatureBank bromotyrosine library
Sign Up to like & getrecommendations! Published in 2022 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.18.164
Abstract: In order to further expand the NatureBank open access compound library, chemical investigations of the Australian marine sponge, Ianthella basta, were undertaken since UHPLC–MS analysis of the extract from this sponge indicated the presence of… read more here.
Keywords: bromotyrosine; library; using uhplc; profiling discovery ... See more keywords