Evaluating groundwater for its probable mutagenicity and genotoxicity using in vitro bioanalytical tools
Sign Up to like & getrecommendations! Published in 2017 at "Exposure and Health"
DOI: 10.1007/s12403-017-0263-9
Abstract: The present study entails the investigation of mutagenic and genotoxic effect of groundwater samples collected from twenty four different locations of Malwa region (India) using in vitro bioassays, viz. Ames fluctuation test (with/without exogenous metabolic… read more here.
Keywords: dna damage; groundwater; water samples; using vitro ... See more keywords
Using in vitro plants to study the cassava response to Xanthomonas phaseoli pv. manihotis infection
Sign Up to like & getrecommendations! Published in 2019 at "Tropical Plant Pathology"
DOI: 10.1007/s40858-019-00296-x
Abstract: Cassava Bacterial Blight (CBB), caused by Xanthomonas phaseoli pv. manihotis (Xpm), is the most important bacterial disease of cassava (Manihot esculenta). Xpm employs Transcription Activator-Like effectors (TALE) to induce the expression of host susceptibility (S)… read more here.
Keywords: vitro plants; phaseoli manihotis; plants study; infection ... See more keywords
Effects of optimal carbohydrases cocktails screened using an in vitro method on nutrient and energy digestibility of different fiber source diets fed to growing pigs
Sign Up to like & getrecommendations! Published in 2020 at "Animal Feed Science and Technology"
DOI: 10.1016/j.anifeedsci.2020.114728
Abstract: Abstract This study aimed to determine the effects of optimal carbohydrases cocktails (OCC) screened using an in vitro method on nutrient and energy digestibility of corn-soybean meal-based diet (CSM), corn-soybean meal-corn distillers dried grains with… read more here.
Keywords: optimal carbohydrases; carbohydrases cocktails; using vitro; screened using ... See more keywords
Digestibility of polymerized whey protein using in vitro digestion model and antioxidative property of its hydrolysate
Sign Up to like & getrecommendations! Published in 2021 at "Food bioscience"
DOI: 10.1016/j.fbio.2021.101109
Abstract: Abstract Polymerized whey protein (PWP) is whey protein aggregates formed by heating whey protein at certain conditions. PWP has been successfully used as thickening agent, fat replacer and microcapsule wall material. However, the digestion properties… read more here.
Keywords: digestion; vitro digestion; using vitro; antioxidative property ... See more keywords
Assessing safety of Lactobacillus plantarum MTCC 5690 and Lactobacillus fermentum MTCC 5689 using in vitro approaches and an in vivo murine model
Sign Up to like & getrecommendations! Published in 2019 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2018.10.011
Abstract: ABSTRACT Lactobacilli have a long history of safe use in human nutrition, however, inclusion of any new strain, despite its safe usage evidence, warrants proper analysis of its safety and toxicity under the purview of… read more here.
Keywords: mtcc 5689; mtcc 5690; safety; using vitro ... See more keywords
Exploring the heterogeneity in glioblastoma cellular mechanics using in-vitro assays and atomic force microscopy
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-04841-4
Abstract: Glioblastoma multiforme (GBM) is an aggressive brain tumor with limited treatment options and prognosis due to its highly invasive nature and therapy resistance. Investigating the nanomechanical and pathophysiological properties of GBM cells will shed light… read more here.
Keywords: glioblastoma; atomic force; mechanics; cell ... See more keywords
Comparative analysis of prebiotic effects of four oligosaccharides using in vitro gut model: digestibility, microbiome, and metabolome changes
Sign Up to like & getrecommendations! Published in 2023 at "FEMS Microbiology Ecology"
DOI: 10.1093/femsec/fiad002
Abstract: Abstract Fructooligosaccharides (FOS), Ad-fructooligosaccharides (Ad-FOS), resistant maltodextrin (RMD), and maltooligosaccharides (MOS) are commercially available prebiotic oligosaccharides. In this study, the effects of prebiotics on the human gut microbial ecosystem were evaluated using an in vitro… read more here.
Keywords: using vitro; vitro gut; rmd; analysis ... See more keywords
Impact of Interfacial Composition on Emulsion Digestion Using In Vitro and In Vivo Models.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of food science"
DOI: 10.1111/1750-3841.14360
Abstract: This study explored the influence of different emulsification layers as mono- and bilayers on lipid digestion by using in vitro and in vivo digestion methods. The monolayer emulsion of rapeseed oil contained whey proteins and the bilayer… read more here.
Keywords: bilayer emulsion; vitro vivo; digestion; using vitro ... See more keywords
Health risk assessment using in vitro simulation in assessing bioavailability of cadmium in rice from main producing areas across China.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food science"
DOI: 10.1111/1750-3841.16158
Abstract: Rice is a recognized source of cadmium (Cd) exposure. In this study, a total of 102 rice samples were obtained from main producing rice regions of China, and the bioavailability of Cd in rice were… read more here.
Keywords: using vitro; health risk; cadmium; bioavailability ... See more keywords
Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio
Sign Up to like & getrecommendations! Published in 2018 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.117.078279
Abstract: (R)-4-((4-(((4-((tetrahydrofuran-3-yl)oxy)benzo[d]isoxazol-3-yl)oxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol (TBPT), a serotonin-4 receptor partial agonist, is metabolized to two metabolites: an N-dealkylation product [(R)-3-(piperidin-4-ylmethoxy)-4-((tetrahydrofuran-3-yl)oxy)benzo[d]isoxazole (M1)] and a cyclized oxazolidine structure [7-(((4-(((R)-tetrahydrofuran-3-yl)oxy)benzo[d]isoxazol-3-yl)oxy)methyl)octahydro-3H (M2)]. After administration of TBPT to humans the exposure to M1 was… read more here.
Keywords: using vitro; ratio; parent drug; drug ... See more keywords
Identification of novel antiviral host factors by functional gene expression analysis using in vitro HBV infection assay systems
Sign Up to like & getrecommendations! Published in 2025 at "PLOS One"
DOI: 10.1371/journal.pone.0314581
Abstract: To cure hepatitis B virus (HBV) infection, it is essential to elucidate the function of hepatocyte host factors in regulating the viral life cycle. Signaling and transcription activator of transcription (STAT)1 play important roles in… read more here.
Keywords: hbv infection; vitro hbv; host; infection ... See more keywords