Articles with "using zebrafish" as a keyword



Bioaccumulation and Biotransformation of BDE‐47 Using Zebrafish Eleutheroembryos (Danio rerio)

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Published in 2023 at "Environmental Toxicology and Chemistry"

DOI: 10.1002/etc.5569

Abstract: Polybrominated diphenyl ethers (PBDEs) are well‐known endocrine disrupting chemicals identified as organic persistent pollutants. Their metabolites OH‐BDE and MeO‐BDE have been reported to be potentially more toxic than the postulated precursor PBDEs. One of the… read more here.

Keywords: biotransformation bde; toxicology; chemistry; bioaccumulation biotransformation ... See more keywords

Deconvolving Passive and Active Targeting of Liposomes Bearing LDL Receptor Binding Peptides Using the Zebrafish Embryo Model.

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Published in 2024 at "Small"

DOI: 10.1002/smll.202310781

Abstract: Improving target versus off-target ratio in nanomedicine remains a major challenge for increasing drug bioavailability and reducing toxicity. Active targeting using ligands on nanoparticle surfaces is a key approach but has limited clinical success. A… read more here.

Keywords: using zebrafish; receptor; zebrafish embryo; embryo model ... See more keywords
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Using Zebrafish to Analyze the Genetic and Environmental Etiologies of Congenital Heart Defects.

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Published in 2020 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-15-2389-2_8

Abstract: Congenital heart defects (CHDs) are among the most common human birth defects. However, the etiology of a large proportion of CHDs remains undefined. Studies identifying the molecular and cellular mechanisms that underlie cardiac development have… read more here.

Keywords: using zebrafish; genetic environmental; congenital heart; heart defects ... See more keywords

Dissecting metabolism using zebrafish models of disease.

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Published in 2019 at "Biochemical Society transactions"

DOI: 10.1042/bst20180335

Abstract: Zebrafish (Danio rerio) are becoming an increasingly powerful model organism to study the role of metabolism in disease. Since its inception, the zebrafish model has relied on unique attributes such as the transparency of embryos,… read more here.

Keywords: metabolism; models disease; using zebrafish; metabolism using ... See more keywords

Using Zebrafish Models to Study Epitranscriptomic Regulation of CNS Functions

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Published in 2025 at "Journal of Neurochemistry"

DOI: 10.1111/jnc.16311

Abstract: Epitranscriptomic regulation of cell functions involves multiple post‐transcriptional chemical modifications of coding and non‐coding RNA that are increasingly recognized in studying human brain disorders. Although rodent models are presently widely used in neuroepitranscriptomic research, the… read more here.

Keywords: using zebrafish; cns; models study; zebrafish models ... See more keywords

Developmental toxicity assessment of Drymaria cordata (Linn.) Willd using zebrafish embryo.

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Published in 2022 at "Current drug safety"

DOI: 10.2174/1574886317666220514153858

Abstract: Drymaria cordata (Linn.) Willd is a creeping herb belonging to the Caryophyllaceae family, widely used as a traditional medicine In Africa and North- east India for various ailments. Many therapeutic applications of D. cordata was… read more here.

Keywords: concentration; drymaria cordata; linn willd; cordata linn ... See more keywords

Assessment of the permeability and toxicity of polymeric nanocapsules using the zebrafish model.

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Published in 2017 at "Nanomedicine"

DOI: 10.2217/nnm-2017-0078

Abstract: AIM To assess the capacity of a new drug delivery nanocapsule (NC) with a double shell of hyaluronic acid and protamine to overcome biological barriers using the zebrafish model. MATERIALS & METHODS NCs were prepared… read more here.

Keywords: toxicity; using zebrafish; assessment permeability; zebrafish model ... See more keywords

Phenotype-based screening of selected mangrove methanolic crude extracts with anti-melanogenic activity using zebrafish (Danio rerio) as a model

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Published in 2017 at "Scienceasia"

DOI: 10.2306/scienceasia1513-1874.2017.43.163

Abstract: Novel skin hypopigmenting agents are important due to the unwanted side effects of existing therapies and treatments. In this study, the melanogenic effects of crude extracts of selected mangroves, namely, Avicennia marina, Excoecaria agallocha, Rhizophora… read more here.

Keywords: using zebrafish; phenotype based; model; crude extracts ... See more keywords

Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model

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Published in 2022 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2022.844568

Abstract: Kif15, a kinesin family member, is powerful in the formation of bipolar spindles. There is emerging evidence indicating that Kif15 plays vital roles in influencing the growth of axons and interference with the progression of… read more here.

Keywords: kif15; system; development; using zebrafish ... See more keywords

Developmental adverse effects of trace amounts of lead: Evaluation using zebrafish model

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1014912

Abstract: Lead (Pb) is widely used as a raw material for various daily necessities in human civilization. However, Pb is a major toxicant and Pb poisoning has long been a global health concern. A large body… read more here.

Keywords: trace amounts; hpf; zebrafish model; developmental adverse ... See more keywords

Using the Zebrafish as a Genetic Model to Study Erythropoiesis

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms221910475

Abstract: Vertebrates generate mature red blood cells (RBCs) via a highly regulated, multistep process called erythropoiesis. Erythropoiesis involves synthesis of heme and hemoglobin, clearance of the nuclei and other organelles, and remodeling of the plasma membrane,… read more here.

Keywords: using zebrafish; genetic model; model study; zebrafish genetic ... See more keywords