USP48 stabilizes gasdermin E to promote pyroptosis in cancer.
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DOI: 10.1158/0008-5472.can-22-1812
Abstract: Pyroptosis is a type of programmed cell death characterized by the activation of inflammatory caspases and the cleavage of gasdermin proteins. Pyroptosis can suppress tumor development and induce anti-tumor immunity, and activating pyroptosis is a… read more here.
Keywords: pyroptosis cancer; stabilizes gasdermin; pyroptosis; usp48 stabilizes ... See more keywords