Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis
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DOI: 10.1038/s41401-019-0249-1
Abstract: Abstractc-Maf is a critical oncogenic transcription factor that contributes to myelomagenesis. Our previous studies demonstrated that the deubiquitinase USP5 stabilizes c-Maf and promotes myeloma cell proliferation and survival; therefore, the USP5/c-Maf axis could be a… read more here.
Keywords: antimyeloma activity; maf; maf axis; axis mebendazole ... See more keywords