Molecular basis of USP7 inhibition by selective small-molecule inhibitors
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature24451
Abstract: Ubiquitination controls the stability of most cellular proteins, and its deregulation contributes to human diseases including cancer. Deubiquitinases remove ubiquitin from proteins, and their inhibition can induce the degradation of selected proteins, potentially including otherwise… read more here.
Keywords: usp7 inhibition; basis usp7; selective small; molecular basis ... See more keywords