Articles with "usp7 usp10" as a keyword



Deubiquitinating Enzymes Ubiquitin-Specific Proteases 7 and 10 Regulate TAU Aggregation

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Published in 2025 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms262211062

Abstract: Accumulation of the microtubule-associated protein TAU into inclusions is a hallmark of tauopathies including Alzheimer’s disease (AD), potentially driven by impaired protein degradation and dysregulated ubiquitination. To explore the role of deubiquitinating enzymes (DUBs), we… read more here.

Keywords: tau aggregation; usp7 usp10; specific proteases; tau ... See more keywords