A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Science"
DOI: 10.1111/cts.13368
Abstract: Little is known about the impact of age on the processes governing human intestinal drug absorption. The Ussing chamber is a system to study drug transport across tissue barriers, but it has not been used… read more here.
Keywords: methodology; ussing chamber; transport; intestinal drug ... See more keywords
The Ussing chamber system for measuring intestinal permeability in health and disease
Sign Up to like & getrecommendations! Published in 2019 at "BMC Gastroenterology"
DOI: 10.1186/s12876-019-1002-4
Abstract: BackgroundThe relationship between intestinal epithelial integrity and the development of intestinal disease is of increasing interest. A reduction in mucosal integrity has been associated with ulcerative colitis, Crohn’s disease and potentially could have links with… read more here.
Keywords: methodology; system; intestinal permeability; ussing chamber ... See more keywords
Interactions Between Emodin and Efflux Transporters on Rat Enterocyte by a Validated Ussing Chamber Technique
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DOI: 10.3389/fphar.2018.00646
Abstract: Emodin, a major active anthraquinone, frequently interacts with other drugs. As changes of efflux transporters on intestine are one of the essential reasons why the drugs interact with each other, a validated Ussing chamber technique… read more here.
Keywords: emodin efflux; ussing chamber; chamber technique; interactions emodin ... See more keywords